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Angiogenesis and anti-angiogenesis in hematological malignancies [electronic resource]

Angiogenesis and anti-angiogenesis in hematological malignancies [electronic resource]

Material type
E-Book(소장)
Personal Author
Ribatti, Domenico, 1956-.
Title Statement
Angiogenesis and anti-angiogenesis in hematological malignancies [electronic resource] / Domenico Ribatti.
Publication, Distribution, etc
Dordrecht :   Springer Netherlands :   Imprint: Springer,   2014.  
Physical Medium
1 online resource (xi, 114 p.) : ill. (some col.).
ISBN
9789401780353
요약
It has been generally accepted that angiogenesis is involved in the pathogenesis of hematological malignancies, like acute and chronic leukemia, lymphoma, myelodysplastic syndromes, myeloproliferative neoplasms and multiple myeloma. The extent of angiogenesis in the bone marrow has been correlated with disease burden, prognosis and treatment outcome. Reciprocal positive and negative interactions between tumor cells and bone marrow stromal cells, namely hematopoietic stem cells, fibroblasts, osteoblasts/osteoclasts, endothelial cells, endothelial progenitor cells, T cells, macrophages and mast cells, mediated by an array of cytokines, receptors and adhesion molecules, modulate the angiogenic response in hematological tumors. More recently, it has been emphasized the pro-angiogenic role of the so called “vascular niche”, indicating a site rich in blood vessels where endothelial cells and mural cells such as pericytes and smooth muscle cells create a microenvironment that affects the behavior of several stem and progenitor cells, in hematological malignancies.
General Note
Title from e-Book title page.  
Content Notes
Preface -- Introduction -- Angiogenesis in multiple myeloma -- Angiogenesis in lymphomas -- Angiogenesis in leukemia -- Antiangiogenesis -- Concluding remarks -- References.
Bibliography, Etc. Note
Includes bibliographical references and index.
이용가능한 다른형태자료
Issued also as a book.  
Subject Added Entry-Topical Term
Leukemia. Neovascularization. Neovascularization inhibitors --Therapeutic use.
Short cut
URL
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100 1 ▼a Ribatti, Domenico, ▼d 1956-.
245 1 0 ▼a Angiogenesis and anti-angiogenesis in hematological malignancies ▼h [electronic resource] / ▼c Domenico Ribatti.
260 ▼a Dordrecht : ▼b Springer Netherlands : ▼b Imprint: Springer, ▼c 2014.
300 ▼a 1 online resource (xi, 114 p.) : ▼b ill. (some col.).
336 ▼a text ▼b txt ▼2 rdacontent
337 ▼a computer ▼b c ▼2 rdamedia
338 ▼a online resource ▼b cr ▼2 rdacarrier
500 ▼a Title from e-Book title page.
504 ▼a Includes bibliographical references and index.
505 0 ▼a Preface -- Introduction -- Angiogenesis in multiple myeloma -- Angiogenesis in lymphomas -- Angiogenesis in leukemia -- Antiangiogenesis -- Concluding remarks -- References.
520 ▼a It has been generally accepted that angiogenesis is involved in the pathogenesis of hematological malignancies, like acute and chronic leukemia, lymphoma, myelodysplastic syndromes, myeloproliferative neoplasms and multiple myeloma. The extent of angiogenesis in the bone marrow has been correlated with disease burden, prognosis and treatment outcome. Reciprocal positive and negative interactions between tumor cells and bone marrow stromal cells, namely hematopoietic stem cells, fibroblasts, osteoblasts/osteoclasts, endothelial cells, endothelial progenitor cells, T cells, macrophages and mast cells, mediated by an array of cytokines, receptors and adhesion molecules, modulate the angiogenic response in hematological tumors. More recently, it has been emphasized the pro-angiogenic role of the so called “vascular niche”, indicating a site rich in blood vessels where endothelial cells and mural cells such as pericytes and smooth muscle cells create a microenvironment that affects the behavior of several stem and progenitor cells, in hematological malignancies.
530 ▼a Issued also as a book.
538 ▼a Mode of access: World Wide Web.
650 0 ▼a Leukemia.
650 0 ▼a Neovascularization.
650 0 ▼a Neovascularization inhibitors ▼x Therapeutic use.
856 4 0 ▼u https://oca.korea.ac.kr/link.n2s?url=http://dx.doi.org/10.1007/978-94-017-8035-3
945 ▼a KLPA
991 ▼a E-Book(소장)

Holdings Information

No. Location Call Number Accession No. Availability Due Date Make a Reservation Service
No. 1 Location Main Library/e-Book Collection/ Call Number CR 616.994061 Accession No. E14035964 Availability Loan can not(reference room) Due Date Make a Reservation Service M

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