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MicroRNAs [electronic resource] : key regulators of oncogenesis

MicroRNAs [electronic resource] : key regulators of oncogenesis

자료유형
E-Book(소장)
개인저자
Babashah, Sadegh.
서명 / 저자사항
MicroRNAs [electronic resource] : key regulators of oncogenesis / Sadegh Babashah, editor.
발행사항
Cham :   Springer International Publishing :   Imprint: Springer,   2014.  
형태사항
1 online resource (xxvi, 433 p.) : ill. (some col.).
ISBN
9783319037257
요약
Aberrant expression and function of microRNAs (miRNAs) in cancer have added a new layer of complexity to the understanding of development and progression of the disease state. It has been demonstrated that miRNAs play a momentous role in oncogenesis via regulating cell proliferation and apoptosis as oncogenes or tumour suppressors. Expression signatures of miRNAs offer exciting opportunities for crafting cutting edge strategies in the diagnosis, prognosis, and therapy of cancer. Since miRNAs can function as either oncogenes or tumor suppressor genes in the tortuous route of oncogenesis, the promise represented by using these small RNAs as therapeutic targets presents new perspectives to the landscape of cancer therapy by either inhibiting or augmenting their activity. This book devotes efforts to provide a broad framework for obtaining an in depth understanding of the state-of-the-art knowledge on abnormalities of miRNAs found to be associated with cancer pathogenesis and possible mechanisms underlying the substantial roles played by miRNAs in cancer development and progression. Also, it intends to pave the way for readers to gain novel insights into using miRNAs as cancer biomarkers and therapeutic platforms.
일반주기
Title from e-Book title page.  
내용주기
Preface -- Part I MicroRNAs: biology and implications in cancer -- MicroRNAs and cancer: an overview -- Epigenetics and microRNA in cancer -- MicroRNA, diet and cancer chemoprevention -- MicroRNAs and energy metabolism in cancer cells -- MicroRNAs and solid tumors -- MicroRNAs and blood cancers -- MicroRNAs and oncogenic human viruses -- MicroRNAs linking cancer and inflammation: focus on liver cancer -- MicroRNAs and regulatory pathways in tumorigenesis -- MicroRNA-modulated apoptotic and autophagic signaling networks in cancer -- MicroRNAs and cancer drug resistance and drug sensitivity -- The biological roles of microRNAs in cancer stem cells -- Part II MicroRNAs and their clinical implications -- MicroRNAs and clinical implications in cancer -- MicroRNA expression profiling and its clinical impact in breast cancer -- MicroRNAs and their clinical impact on resistance to anticancer treatment -- Nanocarriers and microRNA-based scenarios for cancer therapy -- Challenges and strategies for pulmonary delivery of microRNA-based therapeutics -- Abbreviations -- Index.
서지주기
Includes bibliographical references and index.
이용가능한 다른형태자료
Issued also as a book.  
일반주제명
Carcinogenesis. RNA. Medical microbiology. Carcinogenesis. MicroRNAs.
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URL
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020 ▼a 9783319037257
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082 0 0 ▼a 616.99/401 ▼2 23
084 ▼a 616.99401 ▼2 DDCK
090 ▼a 616.99401
245 0 0 ▼a MicroRNAs ▼h [electronic resource] : ▼b key regulators of oncogenesis / ▼c Sadegh Babashah, editor.
260 ▼a Cham : ▼b Springer International Publishing : ▼b Imprint: Springer, ▼c 2014.
300 ▼a 1 online resource (xxvi, 433 p.) : ▼b ill. (some col.).
500 ▼a Title from e-Book title page.
504 ▼a Includes bibliographical references and index.
505 0 ▼a Preface -- Part I MicroRNAs: biology and implications in cancer -- MicroRNAs and cancer: an overview -- Epigenetics and microRNA in cancer -- MicroRNA, diet and cancer chemoprevention -- MicroRNAs and energy metabolism in cancer cells -- MicroRNAs and solid tumors -- MicroRNAs and blood cancers -- MicroRNAs and oncogenic human viruses -- MicroRNAs linking cancer and inflammation: focus on liver cancer -- MicroRNAs and regulatory pathways in tumorigenesis -- MicroRNA-modulated apoptotic and autophagic signaling networks in cancer -- MicroRNAs and cancer drug resistance and drug sensitivity -- The biological roles of microRNAs in cancer stem cells -- Part II MicroRNAs and their clinical implications -- MicroRNAs and clinical implications in cancer -- MicroRNA expression profiling and its clinical impact in breast cancer -- MicroRNAs and their clinical impact on resistance to anticancer treatment -- Nanocarriers and microRNA-based scenarios for cancer therapy -- Challenges and strategies for pulmonary delivery of microRNA-based therapeutics -- Abbreviations -- Index.
520 ▼a Aberrant expression and function of microRNAs (miRNAs) in cancer have added a new layer of complexity to the understanding of development and progression of the disease state. It has been demonstrated that miRNAs play a momentous role in oncogenesis via regulating cell proliferation and apoptosis as oncogenes or tumour suppressors. Expression signatures of miRNAs offer exciting opportunities for crafting cutting edge strategies in the diagnosis, prognosis, and therapy of cancer. Since miRNAs can function as either oncogenes or tumor suppressor genes in the tortuous route of oncogenesis, the promise represented by using these small RNAs as therapeutic targets presents new perspectives to the landscape of cancer therapy by either inhibiting or augmenting their activity. This book devotes efforts to provide a broad framework for obtaining an in depth understanding of the state-of-the-art knowledge on abnormalities of miRNAs found to be associated with cancer pathogenesis and possible mechanisms underlying the substantial roles played by miRNAs in cancer development and progression. Also, it intends to pave the way for readers to gain novel insights into using miRNAs as cancer biomarkers and therapeutic platforms.
530 ▼a Issued also as a book.
538 ▼a Mode of access: World Wide Web.
650 0 ▼a Carcinogenesis.
650 0 ▼a RNA.
650 0 ▼a Medical microbiology.
650 1 2 ▼a Carcinogenesis.
650 1 2 ▼a MicroRNAs.
700 1 ▼a Babashah, Sadegh.
856 4 0 ▼u https://oca.korea.ac.kr/link.n2s?url=http://dx.doi.org/10.1007/978-3-319-03725-7
945 ▼a KLPA
991 ▼a E-Book(소장)

소장정보

No. 소장처 청구기호 등록번호 도서상태 반납예정일 예약 서비스
No. 1 소장처 중앙도서관/e-Book 컬렉션/ 청구기호 CR 616.99401 등록번호 E14033917 도서상태 대출불가(열람가능) 반납예정일 예약 서비스 M

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