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Current advances in osteosarcoma [electronic resource]

Current advances in osteosarcoma [electronic resource]

자료유형
E-Book(소장)
개인저자
Kleinerman, Eugenie.
서명 / 저자사항
Current advances in osteosarcoma [electronic resource] / Eugenie S. Kleinerman, M.D., editor.
발행사항
Cham :   Springer International Publishing :   Imprint: Springer,   2014.  
형태사항
1 online resource (xii, 359 p.) : ill. (some col.).
총서사항
Advances in experimental medicine and biology,0065-2598 ; 804
ISBN
9783319048437
요약
Current Advances in Osteosarcoma summarizes  molecular and genetic characteristics, new therapeutic ideas, and biological characteristics that have been uncovered in this field over the past 10 years. Osteosarcoma is an aggressive malignant neoplasm and is the most common histological form of bone cancer. Osteosarcoma accounts for approximately 56% of new bone tumors, making it the most primary malignant bone tumor in children and adolescents. The lungs are the most common site of metastases and once osteosarcoma spreads to the lungs, it is very difficult to treat.   In order to improve the outcome of this disease, the biology of osteosarcoma needs to be better understood. There are numerous investigators around the world who have made seminal discoveries about the important molecular pathways and genetic alterations that contribute to the development and metastases of osteosarcoma. Other investigators have proposed novel therapeutic strategies including some based on the molecular and genetic phenotype of the disease. This volume will provide a comprehensive review of these new discoveries in one singular text, which will help move the field forward.
일반주기
Title from e-Book title page.  
Includes index.  
내용주기
Historical Perspective on the Introduction and Use of Chemotherapy for the Treatment of Osteosarcoma -- Wnt Signaling in Osteosarcoma -- Receptor Tyrosine Kinases in Osteosarcoma: Not Just the Usual Suspects -- Understanding the Role of Notch in Osteosarcoma -- Developmental Pathways Highjacked by Osteosarcoma -- MicroRNAs in Osteosarcomagenesis -- RECQ DNA Helicases and Osteosarcoma -- Autophagy in Osteosarcoma -- HER-2 Involvement in Osteosarcoma -- Role of Ezrin in Osteosarcoma Metastasis -- Participation of the Fas/FasL Signaling Pathway and the Lung Microenvironment in the Development of Osteosarcoma Lung Metastases -- Zebrafish as a Model for Human Osteosarcoma -- Using Canine Osteosarcoma as a Model to Assess Efficacy of Novel Therapies: Can Old Dogs Teach Us New Tricks? -- Oncolytic Viruses for Potential Osteosarcoma Therapy -- IL-11Rα: A Novel Target for the Treatment of Osteosarcoma -- Bone-seeking Radiopharmaceuticals as Targeted Agents of Osteosarcoma: Samarium-153-EDTMP and Radium-223 -- Muramyl Tripeptide-phophatidyl Ethanolamine Encapsulated in Lipomes (L-MTP-PE) in the Treatment of Osteosarcoma -- Genetically Modified T-cell Therapy for Osteosarcoma -- Natural Killer Cells for Osteosarcoma.
이용가능한 다른형태자료
Issued also as a book.  
일반주제명
Osteosarcoma.
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URL
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020 ▼a 9783319048437
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050 4 ▼a RC261-271
082 0 4 ▼a 616.99/471 ▼2 23
084 ▼a 616.99471 ▼2 DDCK
090 ▼a 616.99471
245 0 0 ▼a Current advances in osteosarcoma ▼h [electronic resource] / ▼c Eugenie S. Kleinerman, M.D., editor.
260 ▼a Cham : ▼b Springer International Publishing : ▼b Imprint: Springer, ▼c 2014.
300 ▼a 1 online resource (xii, 359 p.) : ▼b ill. (some col.).
490 1 ▼a Advances in experimental medicine and biology, ▼x 0065-2598 ; ▼v 804
500 ▼a Title from e-Book title page.
500 ▼a Includes index.
505 0 ▼a Historical Perspective on the Introduction and Use of Chemotherapy for the Treatment of Osteosarcoma -- Wnt Signaling in Osteosarcoma -- Receptor Tyrosine Kinases in Osteosarcoma: Not Just the Usual Suspects -- Understanding the Role of Notch in Osteosarcoma -- Developmental Pathways Highjacked by Osteosarcoma -- MicroRNAs in Osteosarcomagenesis -- RECQ DNA Helicases and Osteosarcoma -- Autophagy in Osteosarcoma -- HER-2 Involvement in Osteosarcoma -- Role of Ezrin in Osteosarcoma Metastasis -- Participation of the Fas/FasL Signaling Pathway and the Lung Microenvironment in the Development of Osteosarcoma Lung Metastases -- Zebrafish as a Model for Human Osteosarcoma -- Using Canine Osteosarcoma as a Model to Assess Efficacy of Novel Therapies: Can Old Dogs Teach Us New Tricks? -- Oncolytic Viruses for Potential Osteosarcoma Therapy -- IL-11Rα: A Novel Target for the Treatment of Osteosarcoma -- Bone-seeking Radiopharmaceuticals as Targeted Agents of Osteosarcoma: Samarium-153-EDTMP and Radium-223 -- Muramyl Tripeptide-phophatidyl Ethanolamine Encapsulated in Lipomes (L-MTP-PE) in the Treatment of Osteosarcoma -- Genetically Modified T-cell Therapy for Osteosarcoma -- Natural Killer Cells for Osteosarcoma.
520 ▼a Current Advances in Osteosarcoma summarizes  molecular and genetic characteristics, new therapeutic ideas, and biological characteristics that have been uncovered in this field over the past 10 years. Osteosarcoma is an aggressive malignant neoplasm and is the most common histological form of bone cancer. Osteosarcoma accounts for approximately 56% of new bone tumors, making it the most primary malignant bone tumor in children and adolescents. The lungs are the most common site of metastases and once osteosarcoma spreads to the lungs, it is very difficult to treat.   In order to improve the outcome of this disease, the biology of osteosarcoma needs to be better understood. There are numerous investigators around the world who have made seminal discoveries about the important molecular pathways and genetic alterations that contribute to the development and metastases of osteosarcoma. Other investigators have proposed novel therapeutic strategies including some based on the molecular and genetic phenotype of the disease. This volume will provide a comprehensive review of these new discoveries in one singular text, which will help move the field forward.
530 ▼a Issued also as a book.
538 ▼a Mode of access: World Wide Web.
650 0 ▼a Osteosarcoma.
700 1 ▼a Kleinerman, Eugenie.
830 0 ▼a Advances in experimental medicine and biology; ▼v 804.
856 4 0 ▼u https://oca.korea.ac.kr/link.n2s?url=http://dx.doi.org/10.1007/978-3-319-04843-7
945 ▼a KLPA
991 ▼a E-Book(소장)

소장정보

No. 소장처 청구기호 등록번호 도서상태 반납예정일 예약 서비스
No. 1 소장처 중앙도서관/e-Book 컬렉션/ 청구기호 CR 616.99471 등록번호 E14033641 도서상태 대출불가(열람가능) 반납예정일 예약 서비스 M

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