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Developments in T cell based cancer immunotherapies [electronic resource]

Developments in T cell based cancer immunotherapies [electronic resource]

Material type
E-Book(소장)
Personal Author
Ascierto, Paolo A. (Paolo Antonio). Stroncek, David F. Wang, Ena.
Title Statement
Developments in T cell based cancer immunotherapies [electronic resource] / Paolo A. Ascierto, David F. Stroncek, Ena Wang, editors.
Publication, Distribution, etc
Cham :   Springer International Publishing :   Imprint: Humana Press,   2015.  
Physical Medium
1 online resource (xv, 305 p.) : col. ill.
Series Statement
Cancer Drug Discovery and Development,2196-9906
ISBN
9783319211671
요약
This volume illustrates the salient aspects of cancer biology relevant to the successful implementation of immunotherapy. Topics include enhancement of antigen-specific immune responses by anti-cancer vaccines, modulation of the function of T cells within the tumor microenvironment, and the effects of genetic, epigenetic, developmental, and environmental determinants on T cell function. Other topics covered include the ex vivo expansion of T or other immune cells and their genetic modification or reprogramming to increase their ability to survive and expand when adoptively transferred back to the patients. Specific attention is devoted to the genetic manipulation of T cells through the introduction of re-directed T cell receptors, chimeric antibody receptors, and other genetic manipulation aimed at improving their effectiveness as anti-cancer agents. Furthermore, the revolutionary role of checkpoint inhibitors and their potential in combination with other immunotherapeutic approaches or with standard chemo and radiation therapy are extensively discussed.
General Note
Title from e-Book title page.  
Content Notes
1 New insight of peptide vaccination in cancer immunotherapy -- 2 The determinants of T cell function for effective anticancer vaccine -- 3 T cell fate in the tumor microenvironment -- 4 T cell receptor avidity and affinity and tumor specific TCR engineer -- 5 Host genetic variation and somatic alteration associated with favorable or compromised T cell function -- 6 Production of Clinical T Cell Therapies -- 7 Clinical success of adoptive cell transfer therapy using tumor infiltrating lymphocytes.-8 Harnessing stem cell-like memory T cells for adoptive cell transfer therapy of cancer -- 9 T cell blockade- anti-CTLA4 immunotherapy against cancer and Abscopal effect in combination therapy -- 10 T cell modulation- anti-OD-1 antibodies for the treatment of cancer -- 11 T cell based therapies in combination with other procedures -- 12 Chimeric antigen receptor T cells CD19 CAR -- 13 Hematopoietic Stem Cell transplantation as immune therapy of malignancies.
Bibliography, Etc. Note
Includes bibliographical references and index.
이용가능한 다른형태자료
Issued also as a book.  
Subject Added Entry-Topical Term
Cancer --Immunotherapy. T cells.
Short cut
URL
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001 000046038280
005 20200727141451
006 m d
007 cr
008 200723s2015 sz a ob 001 0 eng d
020 ▼a 9783319211671
040 ▼a 211009 ▼c 211009 ▼d 211009
082 0 4 ▼a 616.994061 ▼2 23
084 ▼a 616.994061 ▼2 DDCK
090 ▼a 616.994061
245 0 0 ▼a Developments in T cell based cancer immunotherapies ▼h [electronic resource] / ▼c Paolo A. Ascierto, David F. Stroncek, Ena Wang, editors.
260 ▼a Cham : ▼b Springer International Publishing : ▼b Imprint: Humana Press, ▼c 2015.
300 ▼a 1 online resource (xv, 305 p.) : ▼b col. ill.
490 1 ▼a Cancer Drug Discovery and Development, ▼x 2196-9906
500 ▼a Title from e-Book title page.
504 ▼a Includes bibliographical references and index.
505 0 ▼a 1 New insight of peptide vaccination in cancer immunotherapy -- 2 The determinants of T cell function for effective anticancer vaccine -- 3 T cell fate in the tumor microenvironment -- 4 T cell receptor avidity and affinity and tumor specific TCR engineer -- 5 Host genetic variation and somatic alteration associated with favorable or compromised T cell function -- 6 Production of Clinical T Cell Therapies -- 7 Clinical success of adoptive cell transfer therapy using tumor infiltrating lymphocytes.-8 Harnessing stem cell-like memory T cells for adoptive cell transfer therapy of cancer -- 9 T cell blockade- anti-CTLA4 immunotherapy against cancer and Abscopal effect in combination therapy -- 10 T cell modulation- anti-OD-1 antibodies for the treatment of cancer -- 11 T cell based therapies in combination with other procedures -- 12 Chimeric antigen receptor T cells CD19 CAR -- 13 Hematopoietic Stem Cell transplantation as immune therapy of malignancies.
520 ▼a This volume illustrates the salient aspects of cancer biology relevant to the successful implementation of immunotherapy. Topics include enhancement of antigen-specific immune responses by anti-cancer vaccines, modulation of the function of T cells within the tumor microenvironment, and the effects of genetic, epigenetic, developmental, and environmental determinants on T cell function. Other topics covered include the ex vivo expansion of T or other immune cells and their genetic modification or reprogramming to increase their ability to survive and expand when adoptively transferred back to the patients. Specific attention is devoted to the genetic manipulation of T cells through the introduction of re-directed T cell receptors, chimeric antibody receptors, and other genetic manipulation aimed at improving their effectiveness as anti-cancer agents. Furthermore, the revolutionary role of checkpoint inhibitors and their potential in combination with other immunotherapeutic approaches or with standard chemo and radiation therapy are extensively discussed.
530 ▼a Issued also as a book.
538 ▼a Mode of access: World Wide Web.
650 0 ▼a Cancer ▼x Immunotherapy.
650 0 ▼a T cells.
700 1 ▼a Ascierto, Paolo A. ▼q (Paolo Antonio).
700 1 ▼a Stroncek, David F.
700 1 ▼a Wang, Ena.
830 0 ▼a Cancer Drug Discovery and Development.
856 4 0 ▼u https://oca.korea.ac.kr/link.n2s?url=http://dx.doi.org/10.1007/978-3-319-21167-1
945 ▼a KLPA
991 ▼a E-Book(소장)

Holdings Information

No. Location Call Number Accession No. Availability Due Date Make a Reservation Service
No. 1 Location Main Library/e-Book Collection/ Call Number CR 616.994061 Accession No. E14028288 Availability Loan can not(reference room) Due Date Make a Reservation Service M

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