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Neuroanatomy and pathology of sporadic Alzheimer's disease [electronic resource]

Neuroanatomy and pathology of sporadic Alzheimer's disease [electronic resource]

Material type
E-Book(소장)
Personal Author
Braak, Heiko. Del Tredici, Kelly.
Title Statement
Neuroanatomy and pathology of sporadic Alzheimer's disease [electronic resource] / Heiko Braak, Kelly Del Tredici.
Publication, Distribution, etc
Cham :   Springer International Publishing :   Imprint: Springer,   2015.  
Physical Medium
1 online resource (xi, 162 p.) : ill. (some col.).
Series Statement
Advances in anatomy, embryology and cell biology,0301-5556 ; 215
ISBN
9783319126791
요약
As indicated by its title, this monograph deals chiefly with morphologically recognizable deviations from the normal anatomical condition of the human CNS. The AD-associated pathology is illustrated from its beginnings (sometimes even in childhood) to its final form, which is reached late in life. The AD process commences much earlier than the clinically recognizable phase of the disorder, and its timeline includes an extended preclinical phase. The further the pendulum swings away from the symptomatic final stages towards the early pathology, the more obvious the lesions become, although from a standpoint of severity they are more unremarkable and thus frequently overlooked during routine neuropathological assessment. For this reason, the authors deal with the hallmark lesions in the early phases of the AD process in considerable detail.
General Note
Title from e-Book title page.  
Content Notes
Prologue -- General Morphology of Alzheimer-associated intraneuronal pathology -- Consistent and systematic changes in the distribution pattern of intraneuronal inclusions render staging possible -- Basic organization of involved structures -- Presymptomatic stages -- General morphology of Alzheimer-associated extracellular pathology -- Symptomatic stages -- The progression of cortical lesions mimics the pattern of myelination in reverse order -- Tauopathies -- CSF biomarkers and imaging techniques -- The staging hypothesis: assumptions, challenges, potential -- Technical considerations.   
Bibliography, Etc. Note
Includes bibliographical references.
이용가능한 다른형태자료
Issued also as a book.  
Subject Added Entry-Topical Term
Medicine. Alzheimer's disease.
Short cut
URL
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020 ▼a 9783319126791
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050 4 ▼a RC321-580
082 0 4 ▼a 616.831 ▼2 23
084 ▼a 616.831 ▼2 DDCK
090 ▼a 616.831
100 1 ▼a Braak, Heiko.
245 1 0 ▼a Neuroanatomy and pathology of sporadic Alzheimer's disease ▼h [electronic resource] / ▼c Heiko Braak, Kelly Del Tredici.
260 ▼a Cham : ▼b Springer International Publishing : ▼b Imprint: Springer, ▼c 2015.
300 ▼a 1 online resource (xi, 162 p.) : ▼b ill. (some col.).
490 1 ▼a Advances in anatomy, embryology and cell biology, ▼x 0301-5556 ; ▼v 215
500 ▼a Title from e-Book title page.
504 ▼a Includes bibliographical references.
505 0 ▼a Prologue -- General Morphology of Alzheimer-associated intraneuronal pathology -- Consistent and systematic changes in the distribution pattern of intraneuronal inclusions render staging possible -- Basic organization of involved structures -- Presymptomatic stages -- General morphology of Alzheimer-associated extracellular pathology -- Symptomatic stages -- The progression of cortical lesions mimics the pattern of myelination in reverse order -- Tauopathies -- CSF biomarkers and imaging techniques -- The staging hypothesis: assumptions, challenges, potential -- Technical considerations.   
520 ▼a As indicated by its title, this monograph deals chiefly with morphologically recognizable deviations from the normal anatomical condition of the human CNS. The AD-associated pathology is illustrated from its beginnings (sometimes even in childhood) to its final form, which is reached late in life. The AD process commences much earlier than the clinically recognizable phase of the disorder, and its timeline includes an extended preclinical phase. The further the pendulum swings away from the symptomatic final stages towards the early pathology, the more obvious the lesions become, although from a standpoint of severity they are more unremarkable and thus frequently overlooked during routine neuropathological assessment. For this reason, the authors deal with the hallmark lesions in the early phases of the AD process in considerable detail.
530 ▼a Issued also as a book.
538 ▼a Mode of access: World Wide Web.
650 0 ▼a Medicine.
650 0 ▼a Alzheimer's disease.
700 1 ▼a Del Tredici, Kelly.
830 0 ▼a Advances in anatomy, embryology and cell biology; ▼v 215.
856 4 0 ▼u https://oca.korea.ac.kr/link.n2s?url=http://dx.doi.org/10.1007/978-3-319-12679-1
945 ▼a KLPA
991 ▼a E-Book(소장)

Holdings Information

No. Location Call Number Accession No. Availability Due Date Make a Reservation Service
No. 1 Location Main Library/e-Book Collection/ Call Number CR 616.831 Accession No. E14026384 Availability Loan can not(reference room) Due Date Make a Reservation Service M

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