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Pancreatic islets isolation [electronic resource] : from the mouse to the clinic

Pancreatic islets isolation [electronic resource] : from the mouse to the clinic

Material type
E-Book(소장)
Personal Author
Ramírez-Domínguez, Miriam.
Title Statement
Pancreatic islets isolation [electronic resource] : from the mouse to the clinic / Miriam Ramírez-Domínguez, editor.
Publication, Distribution, etc
Cham :   Springer International Publishing :   Imprint: Springer,   2016.  
Physical Medium
1 online resource (xii , 123 p.) : col. ill.
Series Statement
Advances in experimental medicine and biology,0065-2598, 2214-8019 (electronic) ; 938
ISBN
9783319398242
요약
Pancreatic islets make up the endocrine pancreas and they contain the only source of insulin in the body, beta cells. Hence, access to high quality preparations of pancreatic islets is fundamental for in vitro studies and to test pre-clinical applications in animal models in vivo. Access to healthy human islets is also crucial to improve transplantation procedures for diabetes. Given the susceptibility of pancreatic islets to the enzymatic digestion and mechanical stress required to obtain them, the isolation of islets is often considered as the delicate “work of a craftsman”. This book, which is aimed at beginners and experts alike, is a survey of the current state-of–the-art in this field and it centres on the challenges, pitfalls and peculiarities of pancreatic islet isolation in the different species used in pre-clinical and clinical applications. It explores the similarities and differences between human islets and those from other relevant species (rodents, pigs and non-human primates), and how these influence islet isolation. The ultimate goal of this book is to improve the outcome of islet isolation and transplantation in pre-clinical and clinical applications.
General Note
Title from e-Book title page.  
Content Notes
Historical Background of Pancreatic Islet Isolation, Miriam Ramírez-Domínguez -- The Different Faces of the Pancreatic Islets, Midhat H.Abdulreda, Rayner Rodriguez-Diaz, Over Cabrera, Alejandro Caicedo, Per-Olof Berggren -- Isolation of Mouse Pancreatic Islets of Langerhans, Miriam Ramírez-Domínguez -- Pancreatic Islets: Methods for Isolation and Purification of Juvenile and Adult Pig Islets, Heide Brandhorst, Paul R.V. Johnson, Daniel Brandhorst -- Isolation of Pancreatic Islets from NonHuman Primates, Dora M. Berman -- Necessities for a Clinical Islet Program, Wayne John Hawthorne -- Clinical Islet Isolation, Wayne John Hawthorne, Lindy Jane Williams, Yi Vee Chew -- Index.
Bibliography, Etc. Note
Includes bibliographical references and index.
이용가능한 다른형태자료
Issued also as a book.  
Subject Added Entry-Topical Term
Islands of Langerhans. Cell separation.
Short cut
URL
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007 cr
008 200522s2016 sz a ob 001 0 eng d
020 ▼a 9783319398242
040 ▼a 211009 ▼c 211009 ▼d 211009
082 0 4 ▼a 612.34 ▼2 23
084 ▼a 612.34 ▼2 DDCK
090 ▼a 612.34
245 0 0 ▼a Pancreatic islets isolation ▼h [electronic resource] : ▼b from the mouse to the clinic / ▼c Miriam Ramírez-Domínguez, editor.
260 ▼a Cham : ▼b Springer International Publishing : ▼b Imprint: Springer, ▼c 2016.
300 ▼a 1 online resource (xii , 123 p.) : ▼b col. ill.
490 1 ▼a Advances in experimental medicine and biology, ▼x 0065-2598, ▼x 2214-8019 (electronic) ; ▼v 938
500 ▼a Title from e-Book title page.
504 ▼a Includes bibliographical references and index.
505 0 ▼a Historical Background of Pancreatic Islet Isolation, Miriam Ramírez-Domínguez -- The Different Faces of the Pancreatic Islets, Midhat H.Abdulreda, Rayner Rodriguez-Diaz, Over Cabrera, Alejandro Caicedo, Per-Olof Berggren -- Isolation of Mouse Pancreatic Islets of Langerhans, Miriam Ramírez-Domínguez -- Pancreatic Islets: Methods for Isolation and Purification of Juvenile and Adult Pig Islets, Heide Brandhorst, Paul R.V. Johnson, Daniel Brandhorst -- Isolation of Pancreatic Islets from NonHuman Primates, Dora M. Berman -- Necessities for a Clinical Islet Program, Wayne John Hawthorne -- Clinical Islet Isolation, Wayne John Hawthorne, Lindy Jane Williams, Yi Vee Chew -- Index.
520 ▼a Pancreatic islets make up the endocrine pancreas and they contain the only source of insulin in the body, beta cells. Hence, access to high quality preparations of pancreatic islets is fundamental for in vitro studies and to test pre-clinical applications in animal models in vivo. Access to healthy human islets is also crucial to improve transplantation procedures for diabetes. Given the susceptibility of pancreatic islets to the enzymatic digestion and mechanical stress required to obtain them, the isolation of islets is often considered as the delicate “work of a craftsman”. This book, which is aimed at beginners and experts alike, is a survey of the current state-of–the-art in this field and it centres on the challenges, pitfalls and peculiarities of pancreatic islet isolation in the different species used in pre-clinical and clinical applications. It explores the similarities and differences between human islets and those from other relevant species (rodents, pigs and non-human primates), and how these influence islet isolation. The ultimate goal of this book is to improve the outcome of islet isolation and transplantation in pre-clinical and clinical applications.
530 ▼a Issued also as a book.
538 ▼a Mode of access: World Wide Web.
650 0 ▼a Islands of Langerhans.
650 0 ▼a Cell separation.
700 1 ▼a Ramírez-Domínguez, Miriam.
830 0 ▼a Advances in experimental medicine and biology ; ▼v 938.
856 4 0 ▼u https://oca.korea.ac.kr/link.n2s?url=http://dx.doi.org/10.1007/978-3-319-39824-2
945 ▼a KLPA
991 ▼a E-Book(소장)

Holdings Information

No. Location Call Number Accession No. Availability Due Date Make a Reservation Service
No. 1 Location Main Library/e-Book Collection/ Call Number CR 612.34 Accession No. E14022651 Availability Loan can not(reference room) Due Date Make a Reservation Service M

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