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Pancreatic islets isolation [electronic resource] : from the mouse to the clinic

Pancreatic islets isolation [electronic resource] : from the mouse to the clinic

자료유형
E-Book(소장)
개인저자
Ramírez-Domínguez, Miriam.
서명 / 저자사항
Pancreatic islets isolation [electronic resource] : from the mouse to the clinic / Miriam Ramírez-Domínguez, editor.
발행사항
Cham :   Springer International Publishing :   Imprint: Springer,   2016.  
형태사항
1 online resource (xii , 123 p.) : col. ill.
총서사항
Advances in experimental medicine and biology,0065-2598, 2214-8019 (electronic) ; 938
ISBN
9783319398242
요약
Pancreatic islets make up the endocrine pancreas and they contain the only source of insulin in the body, beta cells. Hence, access to high quality preparations of pancreatic islets is fundamental for in vitro studies and to test pre-clinical applications in animal models in vivo. Access to healthy human islets is also crucial to improve transplantation procedures for diabetes. Given the susceptibility of pancreatic islets to the enzymatic digestion and mechanical stress required to obtain them, the isolation of islets is often considered as the delicate “work of a craftsman”. This book, which is aimed at beginners and experts alike, is a survey of the current state-of–the-art in this field and it centres on the challenges, pitfalls and peculiarities of pancreatic islet isolation in the different species used in pre-clinical and clinical applications. It explores the similarities and differences between human islets and those from other relevant species (rodents, pigs and non-human primates), and how these influence islet isolation. The ultimate goal of this book is to improve the outcome of islet isolation and transplantation in pre-clinical and clinical applications.
일반주기
Title from e-Book title page.  
내용주기
Historical Background of Pancreatic Islet Isolation, Miriam Ramírez-Domínguez -- The Different Faces of the Pancreatic Islets, Midhat H.Abdulreda, Rayner Rodriguez-Diaz, Over Cabrera, Alejandro Caicedo, Per-Olof Berggren -- Isolation of Mouse Pancreatic Islets of Langerhans, Miriam Ramírez-Domínguez -- Pancreatic Islets: Methods for Isolation and Purification of Juvenile and Adult Pig Islets, Heide Brandhorst, Paul R.V. Johnson, Daniel Brandhorst -- Isolation of Pancreatic Islets from NonHuman Primates, Dora M. Berman -- Necessities for a Clinical Islet Program, Wayne John Hawthorne -- Clinical Islet Isolation, Wayne John Hawthorne, Lindy Jane Williams, Yi Vee Chew -- Index.
서지주기
Includes bibliographical references and index.
이용가능한 다른형태자료
Issued also as a book.  
일반주제명
Islands of Langerhans. Cell separation.
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020 ▼a 9783319398242
040 ▼a 211009 ▼c 211009 ▼d 211009
082 0 4 ▼a 612.34 ▼2 23
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090 ▼a 612.34
245 0 0 ▼a Pancreatic islets isolation ▼h [electronic resource] : ▼b from the mouse to the clinic / ▼c Miriam Ramírez-Domínguez, editor.
260 ▼a Cham : ▼b Springer International Publishing : ▼b Imprint: Springer, ▼c 2016.
300 ▼a 1 online resource (xii , 123 p.) : ▼b col. ill.
490 1 ▼a Advances in experimental medicine and biology, ▼x 0065-2598, ▼x 2214-8019 (electronic) ; ▼v 938
500 ▼a Title from e-Book title page.
504 ▼a Includes bibliographical references and index.
505 0 ▼a Historical Background of Pancreatic Islet Isolation, Miriam Ramírez-Domínguez -- The Different Faces of the Pancreatic Islets, Midhat H.Abdulreda, Rayner Rodriguez-Diaz, Over Cabrera, Alejandro Caicedo, Per-Olof Berggren -- Isolation of Mouse Pancreatic Islets of Langerhans, Miriam Ramírez-Domínguez -- Pancreatic Islets: Methods for Isolation and Purification of Juvenile and Adult Pig Islets, Heide Brandhorst, Paul R.V. Johnson, Daniel Brandhorst -- Isolation of Pancreatic Islets from NonHuman Primates, Dora M. Berman -- Necessities for a Clinical Islet Program, Wayne John Hawthorne -- Clinical Islet Isolation, Wayne John Hawthorne, Lindy Jane Williams, Yi Vee Chew -- Index.
520 ▼a Pancreatic islets make up the endocrine pancreas and they contain the only source of insulin in the body, beta cells. Hence, access to high quality preparations of pancreatic islets is fundamental for in vitro studies and to test pre-clinical applications in animal models in vivo. Access to healthy human islets is also crucial to improve transplantation procedures for diabetes. Given the susceptibility of pancreatic islets to the enzymatic digestion and mechanical stress required to obtain them, the isolation of islets is often considered as the delicate “work of a craftsman”. This book, which is aimed at beginners and experts alike, is a survey of the current state-of–the-art in this field and it centres on the challenges, pitfalls and peculiarities of pancreatic islet isolation in the different species used in pre-clinical and clinical applications. It explores the similarities and differences between human islets and those from other relevant species (rodents, pigs and non-human primates), and how these influence islet isolation. The ultimate goal of this book is to improve the outcome of islet isolation and transplantation in pre-clinical and clinical applications.
530 ▼a Issued also as a book.
538 ▼a Mode of access: World Wide Web.
650 0 ▼a Islands of Langerhans.
650 0 ▼a Cell separation.
700 1 ▼a Ramírez-Domínguez, Miriam.
830 0 ▼a Advances in experimental medicine and biology ; ▼v 938.
856 4 0 ▼u https://oca.korea.ac.kr/link.n2s?url=http://dx.doi.org/10.1007/978-3-319-39824-2
945 ▼a KLPA
991 ▼a E-Book(소장)

소장정보

No. 소장처 청구기호 등록번호 도서상태 반납예정일 예약 서비스
No. 1 소장처 중앙도서관/e-Book 컬렉션/ 청구기호 CR 612.34 등록번호 E14022651 도서상태 대출불가(열람가능) 반납예정일 예약 서비스 M

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