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Biomarkers for immunotherapy of cancer : methods and protocols

Biomarkers for immunotherapy of cancer : methods and protocols

자료유형
단행본
개인저자
Thurin, Magdalena. Cesano, Alessandra. Marincola, Francesco M.
서명 / 저자사항
Biomarkers for immunotherapy of cancer : methods and protocols / edited by Magdalena Thurin, Alessandra Cesano, Francesco M. Marincola.
발행사항
New York :   Humana Press :   Springer,   c2020.  
형태사항
xviii, 733 p. : co. ill. ; 26 cm.
총서사항
Methods in molecular biology,1064-3745 ; 2055
ISBN
9781493997725
서지주기
Includes bibliographical references and index.
일반주제명
Cancer --Immunotherapy. Biochemical markers.
000 00000nam u2200205 a 4500
001 000046025707
005 20200423180942
008 200423s2020 nyua b 001 0 eng d
020 ▼a 9781493997725
040 ▼a 211009 ▼c 211009 ▼d 211009
082 0 4 ▼a 616.99406 ▼2 23
084 ▼a 616.99406 ▼2 DDCK
090 ▼a 616.99406 ▼b B615
245 0 0 ▼a Biomarkers for immunotherapy of cancer : ▼b methods and protocols / ▼c edited by Magdalena Thurin, Alessandra Cesano, Francesco M. Marincola.
260 ▼a New York : ▼b Humana Press : ▼b Springer, ▼c c2020.
300 ▼a xviii, 733 p. : ▼b co. ill. ; ▼c 26 cm.
490 1 ▼a Methods in molecular biology, ▼x 1064-3745 ; ▼v 2055
490 1 ▼a Springer protocols
504 ▼a Includes bibliographical references and index.
650 0 ▼a Cancer ▼x Immunotherapy.
650 0 ▼a Biochemical markers.
700 1 ▼a Thurin, Magdalena.
700 1 ▼a Cesano, Alessandra.
700 1 ▼a Marincola, Francesco M.
830 0 ▼a Methods in molecular biology ; ▼v 2055.
830 0 ▼a Springer protocols.
945 ▼a KLPA

소장정보

No. 소장처 청구기호 등록번호 도서상태 반납예정일 예약 서비스
No. 1 소장처 과학도서관/Sci-Info(2층서고)/ 청구기호 616.99406 B615 등록번호 121253060 도서상태 대출가능 반납예정일 예약 서비스 B M

컨텐츠정보

목차

Part I: Scientific Questions and the Status of Inhibitory Receptors for Immunotherapy 1. Status of Immune-oncology: Challenges and Opportunities



Alessandra Cesano, Francesco M Marincola, and Magdalena Thurin







2. Immunological Targets for Immunotherapy: Inhibitory T Cell Receptors



Diwakar Davar and Hassane M. Zarour







Part II : Mutational and Germline Profiling 3. Measuring Tumor Mutational Burden Using Whole Exome Sequencing



Tomas Vilimas







4. Germline Genetics in Immuno-Oncology: From Genome-wide to Targeted Biomarker Strategies



Tomas Kirchhoff and Robert Ferguson







5. Detection of Microsatellite Instability Biomarkers via Next-generation Sequencing



Russell Bonneville, Melanie A. Krook, Hui-Zi Chen, Amy Smith, Eric Samorodnitsky, Michele R. Wing, Julie W. Reeser, and Sameek Roychowdhury







6. Genetic Instability Markers in Cancer



Giuseppe Palmieri, Milena Casula, Antonella Manca, Grazia Palomba, Maria Cristina Sini, Valentina Doneddu , Antonio Cossu, and Maria Colombino







7. Validation of Circulating Tumor DNA Assays for Detection of Metastatic Melanoma



Mahrukh M Syeda, Jennifer M. Wiggins, Broderick Corless, Cindy Spittle, George Karlin-Neumann, and David Polsky







8. Techniques Associated with Exosome Isolation for Biomarker Development - Liquid Biopsies for Ovarian Cancer Detection



Shayna Sharma and Carlos Salomon







Part III: Epigenetic Profiling 9. Identifying MicroRNA Pathway Variants as Biomarkers of Patient Selection for Immune Therapy



Joanne B. Weidhaas







10. Histone Modifications as Biomarkers for Immunotherapy



Erin M. Taylor, Brian Koss, Lauren E. Davis, and Alan J. Tackett



Part IV: Functional Genomic Profiling 11. Functional Genome Profiling to Understand Cancer Immune Responsiveness



Ena Wang, Davide Bedognetti, and Francesco M Marincola







12. Using RNA-sequencing to Characterize the Tumor Microenvironment



Smith CC, Bixby LM, Miller KL, Selitsky SR, Bortone DS, Hoadley KA, Vincent BG, and Serody JS



13. Development of Gene Expression Based Biomarkers on the nCounter (R) Platform for Immuno-Oncology Applications



Sarah Warren, Patrick Danaher, Afshin Mashadi-Hossein, Lynell Skewis, Brett Wallden, Sean Ferree, and Alessandra Cesano







14. The CRISPR System and Cancer Immunotherapy Biomarkers



Vitaly Balan and Jianbin Wang







Part V: Phenotyping of Tumor and Immune Cells 15. HLA Class I Antigen Processing Machinery Defects in Cancer Cells - Frequency, Functional Significance and Clinical Relevance with Special Emphasis on their Role in T cell-based Immunotherapy of Malignant Disease



Barbara Seliger and Soldano Ferrone







16. High-parameter Immune Profiling with CyTOF



Bita Sahaf, Adeeb Rahman, Holden T. Maecker, and Sean Bendall







17. The Adaptome as Biomarker for Assessing Cancer Immunity and Immunotherapy



Jian Han and Michael T. Lotze







18. Single Molecule Arrays for Ultrasensitive Detection of Blood-based Biomarkers for Immunotherapy



Limor Cohen, Alissa Keegan, and David R Walt







19. Single-cell Multiplexed Proteomics on the IsoLight Resolves Cellular Functional Heterogeneity to Reveal Clinical Responses of Cancer Patients to Immunotherapies



Dong Liu, Patrick Paczkowski, Sean Mackay, Colin Ng, and Jing Zhou







20. Methods to Detect Immunogenic Cell Death in vivo



Takahiro Yamazaki, Aitziber Buque Martinez, Marissa Rybstein, Jonathan Chen, Ai Sato, and Lorenzo Galluzzi







Part VI: Tissue Imaging Methods 21. Overview of Tissue Imaging Methods



Sanjay S. Patel and Scott J. Rodig







22. Multiplex Immunofluorescence Assays



Alejandro Francisco-Cruz, Edwin Roger Parra, Michael T. Tetzlaff, and Ignacio I. Wistuba,







23. Multiplexed Immunohistochemical Consecutive Staining on Single Slide (MICSSS): Multiplexed Chromogenic IHC Assay for High-Dimensional Tissue Analysis







Guray Akturk, Robert Sweeney, Romain Remark , Miriam Merad, and Sacha Gnjatic



24 Cyclic Multiplexed-Immunofluorescence (cmIF), A Highly Multiplexed Method for Single-cell Analysis



Jennifer Eng, Guillaume Thibault, Shiuh-Wen Luoh, Joe W. Gray, Young Hwan Chang, and Koei Chin







25. High-Plex Spatially Resolved RNA and Protein Detection using Digital Spatial Profiling: A Technology Designed for Immuno-Oncology Biomarker Discovery and Translational Research



Joseph M. Beechem







26. The InSituPlex (R) Staining Method for Multiplexed Immunofluorescence Cell Phenotyping and Spatial Profiling of Tumor FFPE Samples



Mael Manesse, Katir K. Patel, Sean R. Downing, andMark Bobrow







Part VII: Microbiome 27. Microbiome as an Immunological Modifier



Manoj Kumar, Parul Singh, Selvasankar Murugesan, Marie Vetizou, John McCulloch, Jonathan H. Badger, Giorgio Trinchieri, and Souhaila Al Khodor



Part VIII: System Biology for Multi-platform Data Integration 28. Systems Biology for Multi-Platform Data Integration - Overview Elad Ziv



29. Bioinformatics Tools and Resources for Cancer Immunotherapy Study



Alida Palmisano, Julia Krushkal, Ming-Chung Li, Jianwen Fang, Dmitriy Sonkin, George Wright, Laura Yee, Yingdong Zhao, Lisa McShane







30. Multiplatform Integrative Analysis of Immunogenomic Data for Biomarker Discovery



Vesteinn Thorsson




Part IX: Regulatory Perspective 31. Translating Immuno-Oncology Biomarkers to Diagnostic tests: A Regulatory Perspective



You Li, Janaki Veeraraghavan, and Reena Philip

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