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Patient-derived xenograft models of human cancer [electronic resource]

Patient-derived xenograft models of human cancer [electronic resource]

Material type
E-Book(소장)
Personal Author
Wang, Yuzhuo. Lin, Dong. Gout, Peter W.
Title Statement
Patient-derived xenograft models of human cancer [electronic resource] / Yuzhuo Wang, Dong Lin, Peter W. Gout, editors.
Publication, Distribution, etc
Cham :   Springer,   2017.  
Physical Medium
1 online resource (xi, 204 p.) : ill. (chiefly col.).
Series Statement
Molecular and translational medicine,2197-7852
ISBN
9783319558240 9783319558257 (eBook)
요약
This book provides a comprehensive, state-of-the-art review of PDX cancer models. In separately produced chapters, the history and evolution of PDX models is reviewed, methods of PDX model development are compared in detail, characteristics of available established models are presented, current applications are summarized and new perspectives about use of PDX models are proposed. Each chapter is written by a world-renowned expert who is conducting cutting-edge research in the field. Each of the subsections provide a comprehensive review of existing literature addressing the particular topic followed by a conclusive paragraph detailing future directions. Extensive illustrations make this an interactive text. Patient-Derived Xenograft Models of Human Cancer will serve as a highly useful resource for researchers and clinicians dealing with, or interested in, this important topic. It will provide a concise yet comprehensive summary of the current status of the field that will help guide preclinical and clinical applications as well as stimulate investigative efforts. This book will propagate innovative concepts and prompt the development of ground-breaking technological solutions in this field.
General Note
Title from e-Book title page.  
Content Notes
Introduction -- History and Evolution of PDX Cancer Models -- Establishment and Characterization of PDX Models -- Methods of Generating PDX Models -- Fidelity and Stability of PDX Models -- Applications of PDX Models -- Studies of Cancer Heterogeneity -- PDX and Cancer Stem Cells -- Modeling Cancer Metastasis -- Modeling Drug Resistance -- PDX and Biomarker Development -- PDX and Preclinical Drug Screening -- Co-clinical Trials and Personalized Cancer Therapy/Precision Medicine -- Epilogue -- Future Perspective.
Bibliography, Etc. Note
Includes bibliographical references and index.
이용가능한 다른형태자료
Issued also as a book.  
Subject Added Entry-Topical Term
Cancer --Simulation methods. Cancer --Research.
Short cut
URL
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020 ▼a 9783319558240
020 ▼a 9783319558257 (eBook)
040 ▼a 211009 ▼c 211009 ▼d 211009
050 4 ▼a RC254-282
082 0 4 ▼a 616.9940011 ▼2 23
084 ▼a 616.9940011 ▼2 DDCK
090 ▼a 616.9940011
245 0 0 ▼a Patient-derived xenograft models of human cancer ▼h [electronic resource] / ▼c Yuzhuo Wang, Dong Lin, Peter W. Gout, editors.
260 ▼a Cham : ▼b Springer, ▼c 2017.
300 ▼a 1 online resource (xi, 204 p.) : ▼b ill. (chiefly col.).
490 1 ▼a Molecular and translational medicine, ▼x 2197-7852
500 ▼a Title from e-Book title page.
504 ▼a Includes bibliographical references and index.
505 0 ▼a Introduction -- History and Evolution of PDX Cancer Models -- Establishment and Characterization of PDX Models -- Methods of Generating PDX Models -- Fidelity and Stability of PDX Models -- Applications of PDX Models -- Studies of Cancer Heterogeneity -- PDX and Cancer Stem Cells -- Modeling Cancer Metastasis -- Modeling Drug Resistance -- PDX and Biomarker Development -- PDX and Preclinical Drug Screening -- Co-clinical Trials and Personalized Cancer Therapy/Precision Medicine -- Epilogue -- Future Perspective.
520 ▼a This book provides a comprehensive, state-of-the-art review of PDX cancer models. In separately produced chapters, the history and evolution of PDX models is reviewed, methods of PDX model development are compared in detail, characteristics of available established models are presented, current applications are summarized and new perspectives about use of PDX models are proposed. Each chapter is written by a world-renowned expert who is conducting cutting-edge research in the field. Each of the subsections provide a comprehensive review of existing literature addressing the particular topic followed by a conclusive paragraph detailing future directions. Extensive illustrations make this an interactive text. Patient-Derived Xenograft Models of Human Cancer will serve as a highly useful resource for researchers and clinicians dealing with, or interested in, this important topic. It will provide a concise yet comprehensive summary of the current status of the field that will help guide preclinical and clinical applications as well as stimulate investigative efforts. This book will propagate innovative concepts and prompt the development of ground-breaking technological solutions in this field.
530 ▼a Issued also as a book.
538 ▼a Mode of access: World Wide Web.
650 0 ▼a Cancer ▼x Simulation methods.
650 0 ▼a Cancer ▼x Research.
700 1 ▼a Wang, Yuzhuo.
700 1 ▼a Lin, Dong.
700 1 ▼a Gout, Peter W.
830 0 ▼a Molecular and translational medicine.
856 4 0 ▼u https://oca.korea.ac.kr/link.n2s?url=https://doi.org/10.1007/978-3-319-55825-7
945 ▼a KLPA
991 ▼a E-Book(소장)

Holdings Information

No. Location Call Number Accession No. Availability Due Date Make a Reservation Service
No. 1 Location Main Library/e-Book Collection/ Call Number CR 616.9940011 Accession No. E14016413 Availability Loan can not(reference room) Due Date Make a Reservation Service M

Contents information

Table of Contents

Section I: Introduction History and Evolution of PDX Cancer Models Section II: Establishment and Characterization of PDX Models Methods of Generating PDX Models Fidelity and Stability of PDX Models Section III: Applications of PDX Models Studies of Cancer Heterogeneity PDX and Cancer Stem Cells Modeling Cancer Metastasis Modeling Drug Resistance PDX and Biomarker Development PDX and Preclinical Drug Screening Co-clinical Trials and Personalized Cancer Therapy/Precision Medicine Section IV: Epilogue Future Perspective.


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