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Biomarkers for endometriosis [electronic resource] : state of the art

Biomarkers for endometriosis [electronic resource] : state of the art

자료유형
E-Book(소장)
개인저자
D'Hooghe, Thomas.
서명 / 저자사항
Biomarkers for endometriosis [electronic resource] : state of the art / Thomas D'Hooghe, editor.
발행사항
Cham :   Springer,   c2017.  
형태사항
1 online resource (xii, 267 p.) : ill.
ISBN
9783319598543 9783319598567 (e-book)
요약
This book presents an overview of the diagnostic performance of non- or semi-invasive tests for endometriosis in peripheral blood, endometrium, saliva, peritoneal fluid and urine. The value of existing and emerging systems biology technologies for biomarker development is addressed in several chapters on genetics, microarrays, proteomics and metabolomics. Although tests with high sensitivity and acceptable specificity have been developed, sometimes validated in independent populations and seem promising, more research is needed to translate these data into clinical benefit for patients and coordinate efforts internationally to standarize analysis, reports and operating procedures. The gold standard to diagnose endometriosis is currently through laparoscopic inspection with histological confirmation, a surgical procedure with rare but significant potential risks for the patients. A non-invasive test for endometriosis would be critical for the early detection of endometriosis of symptomatic women with pelvic pain and/or subfertility with normal ultrasound. This would include nearly all cases of minimal-mild endometriosis, some cases of moderate-severe endometriosis without a clearly visible ovarian endometrioma and cases with pelvic adhesions and/or other pelvic pathology, who might benefit from surgery to improve pelvic pain and/or subfertility. Such a test would also be useful in symptomatic women with ultrasound imaging suspicious for endometriosis, since it may be difficult to differentiate an ovarian endometrioma from other ovarian cysts and since the quality of ultrasound imaging is highly variable worldwide.
일반주기
Title from e-Book title page.  
내용주기
Biomarker development: general concepts and state of the art in medicine -- Biomarker development in chronic inflammatory diseases -- Biomarker development in cancer -- Biomarker development in ovarian cancer -- Biomarker development in  endometrial cancer -- Biomarker development in breast cancer -- Biomarker development in reproductive medicine -- Industry perspective on biomarker development in medicine -- Biomarker development in endometriosis -- Health economic impact of endometriosis -- Patient perspective on biomarker development for endometriosis -- Genetic biomarkers for endometriosis -- Epidemiological and clinical risk factors for endometriosis -- Peripheral blood biomarkers for endometriosis -- Endometrial biomarkers for endometriosis -- Biomarkers for endometriosis in saliva, urine and peritoneal fluid -- mRNA and miRNA biomarkers for endometriosis -- Proteomic biomarkers for endometriosis -- Multiprotein arrays and endometriosis -- Metabolomics and endometriosis -- Harmonization of clinical and laboratory data to improve biomarker discovery in endometriosis -- Endometriomics and biomarker development  in endometriosis.
서지주기
Includes bibliographical references and index.
이용가능한 다른형태자료
Issued also as a book.  
일반주제명
Endometriosis --Diagnosis. Biochemical markers.
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020 ▼a 9783319598543
020 ▼a 9783319598567 (e-book)
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245 0 0 ▼a Biomarkers for endometriosis ▼h [electronic resource] : ▼b state of the art / ▼c Thomas D'Hooghe, editor.
260 ▼a Cham : ▼b Springer, ▼c c2017.
300 ▼a 1 online resource (xii, 267 p.) : ▼b ill.
500 ▼a Title from e-Book title page.
504 ▼a Includes bibliographical references and index.
505 0 ▼a Biomarker development: general concepts and state of the art in medicine -- Biomarker development in chronic inflammatory diseases -- Biomarker development in cancer -- Biomarker development in ovarian cancer -- Biomarker development in  endometrial cancer -- Biomarker development in breast cancer -- Biomarker development in reproductive medicine -- Industry perspective on biomarker development in medicine -- Biomarker development in endometriosis -- Health economic impact of endometriosis -- Patient perspective on biomarker development for endometriosis -- Genetic biomarkers for endometriosis -- Epidemiological and clinical risk factors for endometriosis -- Peripheral blood biomarkers for endometriosis -- Endometrial biomarkers for endometriosis -- Biomarkers for endometriosis in saliva, urine and peritoneal fluid -- mRNA and miRNA biomarkers for endometriosis -- Proteomic biomarkers for endometriosis -- Multiprotein arrays and endometriosis -- Metabolomics and endometriosis -- Harmonization of clinical and laboratory data to improve biomarker discovery in endometriosis -- Endometriomics and biomarker development  in endometriosis.
520 ▼a This book presents an overview of the diagnostic performance of non- or semi-invasive tests for endometriosis in peripheral blood, endometrium, saliva, peritoneal fluid and urine. The value of existing and emerging systems biology technologies for biomarker development is addressed in several chapters on genetics, microarrays, proteomics and metabolomics. Although tests with high sensitivity and acceptable specificity have been developed, sometimes validated in independent populations and seem promising, more research is needed to translate these data into clinical benefit for patients and coordinate efforts internationally to standarize analysis, reports and operating procedures. The gold standard to diagnose endometriosis is currently through laparoscopic inspection with histological confirmation, a surgical procedure with rare but significant potential risks for the patients. A non-invasive test for endometriosis would be critical for the early detection of endometriosis of symptomatic women with pelvic pain and/or subfertility with normal ultrasound. This would include nearly all cases of minimal-mild endometriosis, some cases of moderate-severe endometriosis without a clearly visible ovarian endometrioma and cases with pelvic adhesions and/or other pelvic pathology, who might benefit from surgery to improve pelvic pain and/or subfertility. Such a test would also be useful in symptomatic women with ultrasound imaging suspicious for endometriosis, since it may be difficult to differentiate an ovarian endometrioma from other ovarian cysts and since the quality of ultrasound imaging is highly variable worldwide.
530 ▼a Issued also as a book.
538 ▼a Mode of access: World Wide Web.
650 0 ▼a Endometriosis ▼x Diagnosis.
650 0 ▼a Biochemical markers.
700 1 ▼a D'Hooghe, Thomas.
856 4 0 ▼u https://oca.korea.ac.kr/link.n2s?url=https://doi.org/10.1007/978-3-319-59856-7
945 ▼a KLPA
991 ▼a E-Book(소장)

소장정보

No. 소장처 청구기호 등록번호 도서상태 반납예정일 예약 서비스
No. 1 소장처 중앙도서관/e-Book 컬렉션/ 청구기호 CR 618.1075 등록번호 E14015386 도서상태 대출불가(열람가능) 반납예정일 예약 서비스 M

컨텐츠정보

목차

Biomarker development: general concepts and state of the art in medicine
Biomarker development in chronic inflammatory diseases
Biomarker development in cancer
Biomarker development in ovarian cancer
Biomarker development in  endometrial cancer
Biomarker development in breast cancer
Biomarker development in reproductive medicine
Industry perspective on biomarker development in medicine
Biomarker development in endometriosis
Health economic impact of endometriosis
Patient perspective on biomarker development for endometriosis
Genetic biomarkers for endometriosis
Epidemiological and clinical risk factors for endometriosis
Peripheral blood biomarkers for endometriosis
Endometrial biomarkers for endometriosis
Biomarkers for endometriosis in saliva, urine and peritoneal fluid
mRNA and miRNA biomarkers for endometriosis
Proteomic biomarkers for endometriosis
Multiprotein arrays and endometriosis
Metabolomics and endometriosis
Harmonization of clinical and laboratory data to improve biomarker discovery in endometriosis
Endometriomics and biomarker development  in endometriosis.

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