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Animal models of neurological disorders [electronic resource] : principle and working procedure for animal models of neurological disorders

Animal models of neurological disorders [electronic resource] : principle and working procedure for animal models of neurological disorders

Material type
E-Book(소장)
Personal Author
Bansal, Puneet Kumar. Deshmukh, Rahul.
Title Statement
Animal models of neurological disorders [electronic resource] : principle and working procedure for animal models of neurological disorders / Puneet Kumar Bansal, Rahul Deshmukh, editors.
Publication, Distribution, etc
Singapore :   Springer,   c2017.  
Physical Medium
1 online resource (xviii, 343 p.) : ill.
ISBN
9789811059803 9789811059810 (e-book)
요약
This book introduces undergraduate, postgraduate and research students and scientists to animal models of neurological disorders, along with their working principle and brief procedures. Addressing all the disorders related to the central nervous system (CNS) in a single platform, on the basis of various literature surveys it describes different procedures to induce a single disease with the help of toxins/chemicals. It also includes numerous protocols for inducing single neurological diseases, thus fulfilling an urgent need for a book that makes specific procedures for neurological disorders available, so that specific disease can be induced in laboratories according to the availability of resources. Further, it acquaints readers with the pathological changes that occur in a particular neurological disorder, which reflect specific signs and symptoms of any particular disease, and examines how they affect everyday life. It is a valuable resource for researchers aiming to eradicate or improve neurological disorders by testing the benefits of different drugs.
General Note
Title from e-Book title page.  
Content Notes
Introduction -- Behavioral observation in neurological disorders -- Anesthesia used in experimental laboratory -- Euthanasia procedure used in experimental laboratory -- Animal models of Epilepsy -- Animal models of Alzheimer’s -- Animal models of Parkinson's -- Animal models of Huntington's -- Animal models of Stroke and Traumatic brain injury -- Animal models of Migraine -- Animal models of Antipsychotics (Schizophrenia).
Bibliography, Etc. Note
Includes bibliographical references and index.
이용가능한 다른형태자료
Issued also as a book.  
Subject Added Entry-Topical Term
Neurosciences. Laboratory animals. Neurobiology. Toxicology.
Short cut
URL
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020 ▼a 9789811059803
020 ▼a 9789811059810 (e-book)
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050 4 ▼a RC321-580
082 0 4 ▼a 616.8027 ▼2 23
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090 ▼a 616.8027
245 0 0 ▼a Animal models of neurological disorders ▼h [electronic resource] : ▼b principle and working procedure for animal models of neurological disorders / ▼c Puneet Kumar Bansal, Rahul Deshmukh, editors.
260 ▼a Singapore : ▼b Springer, ▼c c2017.
300 ▼a 1 online resource (xviii, 343 p.) : ▼b ill.
500 ▼a Title from e-Book title page.
504 ▼a Includes bibliographical references and index.
505 0 ▼a Introduction -- Behavioral observation in neurological disorders -- Anesthesia used in experimental laboratory -- Euthanasia procedure used in experimental laboratory -- Animal models of Epilepsy -- Animal models of Alzheimer’s -- Animal models of Parkinson's -- Animal models of Huntington's -- Animal models of Stroke and Traumatic brain injury -- Animal models of Migraine -- Animal models of Antipsychotics (Schizophrenia).
520 ▼a This book introduces undergraduate, postgraduate and research students and scientists to animal models of neurological disorders, along with their working principle and brief procedures. Addressing all the disorders related to the central nervous system (CNS) in a single platform, on the basis of various literature surveys it describes different procedures to induce a single disease with the help of toxins/chemicals. It also includes numerous protocols for inducing single neurological diseases, thus fulfilling an urgent need for a book that makes specific procedures for neurological disorders available, so that specific disease can be induced in laboratories according to the availability of resources. Further, it acquaints readers with the pathological changes that occur in a particular neurological disorder, which reflect specific signs and symptoms of any particular disease, and examines how they affect everyday life. It is a valuable resource for researchers aiming to eradicate or improve neurological disorders by testing the benefits of different drugs.
530 ▼a Issued also as a book.
538 ▼a Mode of access: World Wide Web.
650 0 ▼a Neurosciences.
650 0 ▼a Laboratory animals.
650 0 ▼a Neurobiology.
650 0 ▼a Toxicology.
700 1 ▼a Bansal, Puneet Kumar.
700 1 ▼a Deshmukh, Rahul.
856 4 0 ▼u https://oca.korea.ac.kr/link.n2s?url=https://doi.org/10.1007/978-981-10-5981-0
945 ▼a KLPA
991 ▼a E-Book(소장)

Holdings Information

No. Location Call Number Accession No. Availability Due Date Make a Reservation Service
No. 1 Location Main Library/e-Book Collection/ Call Number CR 616.8027 Accession No. E14014564 Availability Loan can not(reference room) Due Date Make a Reservation Service M

Contents information

Table of Contents

Intro -- Preface and Acknowledgements -- Contents -- Editors and Contributors -- Abbreviations -- 1 Introduction -- 2 Non-transgenic Animal Models of Alzheimer’s Disease -- 1 Introduction -- 2 Classification of Models AD -- 2.1 Chemical-Induced AD Models -- 2.1.1 STZ-Induced AD -- 2.1.2 Amyloid Beta-Induced AD -- Clinical Relevance -- 2.1.3 Colchicine-Induced AD -- 2.2 Metal-Induced AD -- 2.2.1 Aluminum-Induced AD -- 2.2.2 Aluminum-, Aβ- and Transforming Growth Factor Beta-1(Tgfβ-1)-Induced AD -- 2.2.3 AlCl3- and D-Galactose-Induced AD -- 2.2.4 Zinc-Induced AD -- 2.3 Lipids-Induced AD -- 2.3.1 Cholesterol-Induced AD -- 2.3.2 Lipopolysaccharides-Induced AD -- 2.4 Aging-Induced AD -- 2.4.1 D-Galactose-Induced AD -- 3 Conclusion -- References -- 3 Animal Models of Parkinson’s Disease -- 1 Introduction -- 2 Classification of Animal Models of PD (Fig. 1) -- 2.1 Toxin-Induced Models -- 2.1.1 6-Hydroxy Dopamine (6-OHDA)-Induced Parkinsonism -- 2.1.2 Mitochondrial Complex I (NADPH Dehydrogenase) Inhibitors -- MPTP-Induced Neurotoxicity -- Rotenone-Induced Parkinsonism -- Paraquat-Induced Parkinsonism -- Maneb-Induced PD -- 2.1.3 Metal-Induced Parkinsonism -- Manganese -- 2.1.4 Neuro-inflammatory Models -- LPS-Induced Parkinsonism -- 2.2 Drug-Induced Parkinsonism -- 2.2.1 Antipsychotic Drugs-Induced Parkinsonism -- Haloperidol -- Flufenazine -- 2.2.2 Indole Alkaloids-Induced Parkinsonism -- Reserpine -- Harmaline -- 2.2.3 CNS Stimulants -- Methamphetamine -- 2.2.4 Anti-emetics-Induced Parkinsonism -- Metoclopramide -- 2.3 Others Models of PD -- 2.3.1 Drosophila as a Model of PD -- 2.3.2 Zebrafish as a New Model for PD -- 2.3.3 Encephalitis Virus-Induced PD -- 3 Conclusion -- References -- 4 Animal Models of Huntington’s Disease -- 1 Introduction -- 2 Classification of Animal Models -- 2.1 Toxin Models -- 2.1.1 Energy Metabolism Deficit Models -- 3-Nitropropionic Acid Model -- Malonic Acid Model -- 2.1.2 Excitotoxin Models -- Kainic Acid Model -- Quinolinic Acid Model -- 2.2 Nonhuman Primate Models -- 3 Conclusion -- References -- 5 Animal Models of Epilepsy -- 1 Introduction -- 2 Need of Animal Models -- 2.1 Characteristics of an Ideal Animal Model of Epilepsy -- 2.2 Score -- 3 Classification of Seizure -- 4 Pathophysiology of Seizures -- 5 Classification of Animal Models of Epilepsy (Fig. 3) -- 5.1 Chemical-Induced Convulsions -- 5.1.1 Pentylenetetrazol-Induced Convulsions -- 5.1.2 Bicuculline-Induced Convulsions -- 5.1.3 Strychnine-Induced Convulsions -- 5.1.4 Picrotoxin-Induced Convulsions -- 5.1.5 Kainic Acid-Induced Convulsions -- 5.1.6 Tetanus Toxin-Induced Convulsions -- 5.1.7 Penicillin-Induced Convulsions -- 6 Model of Status Epilepticus -- 6.1 Lithium-Pilocarpine Model of Status Epilepticus -- 6.2 Perforant Path Stimulation Model of Status Epilepticus -- 7 Maximal Electroshock (MES)-Induced Convulsions -- 8 Animal Models of Temporal Lobe Epilepsy -- 8.1 Amygdala Kindling -- 8.2 Hippocampal Kindling -- 8.3 Corneal Kindling -- 8.4 Piriform Cortex .

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