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Animal models of neurological disorders [electronic resource] : principle and working procedure for animal models of neurological disorders

Animal models of neurological disorders [electronic resource] : principle and working procedure for animal models of neurological disorders

자료유형
E-Book(소장)
개인저자
Bansal, Puneet Kumar. Deshmukh, Rahul.
서명 / 저자사항
Animal models of neurological disorders [electronic resource] : principle and working procedure for animal models of neurological disorders / Puneet Kumar Bansal, Rahul Deshmukh, editors.
발행사항
Singapore :   Springer,   c2017.  
형태사항
1 online resource (xviii, 343 p.) : ill.
ISBN
9789811059803 9789811059810 (e-book)
요약
This book introduces undergraduate, postgraduate and research students and scientists to animal models of neurological disorders, along with their working principle and brief procedures. Addressing all the disorders related to the central nervous system (CNS) in a single platform, on the basis of various literature surveys it describes different procedures to induce a single disease with the help of toxins/chemicals. It also includes numerous protocols for inducing single neurological diseases, thus fulfilling an urgent need for a book that makes specific procedures for neurological disorders available, so that specific disease can be induced in laboratories according to the availability of resources. Further, it acquaints readers with the pathological changes that occur in a particular neurological disorder, which reflect specific signs and symptoms of any particular disease, and examines how they affect everyday life. It is a valuable resource for researchers aiming to eradicate or improve neurological disorders by testing the benefits of different drugs.
일반주기
Title from e-Book title page.  
내용주기
Introduction -- Behavioral observation in neurological disorders -- Anesthesia used in experimental laboratory -- Euthanasia procedure used in experimental laboratory -- Animal models of Epilepsy -- Animal models of Alzheimer’s -- Animal models of Parkinson's -- Animal models of Huntington's -- Animal models of Stroke and Traumatic brain injury -- Animal models of Migraine -- Animal models of Antipsychotics (Schizophrenia).
서지주기
Includes bibliographical references and index.
이용가능한 다른형태자료
Issued also as a book.  
일반주제명
Neurosciences. Laboratory animals. Neurobiology. Toxicology.
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245 0 0 ▼a Animal models of neurological disorders ▼h [electronic resource] : ▼b principle and working procedure for animal models of neurological disorders / ▼c Puneet Kumar Bansal, Rahul Deshmukh, editors.
260 ▼a Singapore : ▼b Springer, ▼c c2017.
300 ▼a 1 online resource (xviii, 343 p.) : ▼b ill.
500 ▼a Title from e-Book title page.
504 ▼a Includes bibliographical references and index.
505 0 ▼a Introduction -- Behavioral observation in neurological disorders -- Anesthesia used in experimental laboratory -- Euthanasia procedure used in experimental laboratory -- Animal models of Epilepsy -- Animal models of Alzheimer’s -- Animal models of Parkinson's -- Animal models of Huntington's -- Animal models of Stroke and Traumatic brain injury -- Animal models of Migraine -- Animal models of Antipsychotics (Schizophrenia).
520 ▼a This book introduces undergraduate, postgraduate and research students and scientists to animal models of neurological disorders, along with their working principle and brief procedures. Addressing all the disorders related to the central nervous system (CNS) in a single platform, on the basis of various literature surveys it describes different procedures to induce a single disease with the help of toxins/chemicals. It also includes numerous protocols for inducing single neurological diseases, thus fulfilling an urgent need for a book that makes specific procedures for neurological disorders available, so that specific disease can be induced in laboratories according to the availability of resources. Further, it acquaints readers with the pathological changes that occur in a particular neurological disorder, which reflect specific signs and symptoms of any particular disease, and examines how they affect everyday life. It is a valuable resource for researchers aiming to eradicate or improve neurological disorders by testing the benefits of different drugs.
530 ▼a Issued also as a book.
538 ▼a Mode of access: World Wide Web.
650 0 ▼a Neurosciences.
650 0 ▼a Laboratory animals.
650 0 ▼a Neurobiology.
650 0 ▼a Toxicology.
700 1 ▼a Bansal, Puneet Kumar.
700 1 ▼a Deshmukh, Rahul.
856 4 0 ▼u https://oca.korea.ac.kr/link.n2s?url=https://doi.org/10.1007/978-981-10-5981-0
945 ▼a KLPA
991 ▼a E-Book(소장)

소장정보

No. 소장처 청구기호 등록번호 도서상태 반납예정일 예약 서비스
No. 1 소장처 중앙도서관/e-Book 컬렉션/ 청구기호 CR 616.8027 등록번호 E14014564 도서상태 대출불가(열람가능) 반납예정일 예약 서비스 M

컨텐츠정보

목차

Intro -- Preface and Acknowledgements -- Contents -- Editors and Contributors -- Abbreviations -- 1 Introduction -- 2 Non-transgenic Animal Models of Alzheimer’s Disease -- 1 Introduction -- 2 Classification of Models AD -- 2.1 Chemical-Induced AD Models -- 2.1.1 STZ-Induced AD -- 2.1.2 Amyloid Beta-Induced AD -- Clinical Relevance -- 2.1.3 Colchicine-Induced AD -- 2.2 Metal-Induced AD -- 2.2.1 Aluminum-Induced AD -- 2.2.2 Aluminum-, Aβ- and Transforming Growth Factor Beta-1(Tgfβ-1)-Induced AD -- 2.2.3 AlCl3- and D-Galactose-Induced AD -- 2.2.4 Zinc-Induced AD -- 2.3 Lipids-Induced AD -- 2.3.1 Cholesterol-Induced AD -- 2.3.2 Lipopolysaccharides-Induced AD -- 2.4 Aging-Induced AD -- 2.4.1 D-Galactose-Induced AD -- 3 Conclusion -- References -- 3 Animal Models of Parkinson’s Disease -- 1 Introduction -- 2 Classification of Animal Models of PD (Fig. 1) -- 2.1 Toxin-Induced Models -- 2.1.1 6-Hydroxy Dopamine (6-OHDA)-Induced Parkinsonism -- 2.1.2 Mitochondrial Complex I (NADPH Dehydrogenase) Inhibitors -- MPTP-Induced Neurotoxicity -- Rotenone-Induced Parkinsonism -- Paraquat-Induced Parkinsonism -- Maneb-Induced PD -- 2.1.3 Metal-Induced Parkinsonism -- Manganese -- 2.1.4 Neuro-inflammatory Models -- LPS-Induced Parkinsonism -- 2.2 Drug-Induced Parkinsonism -- 2.2.1 Antipsychotic Drugs-Induced Parkinsonism -- Haloperidol -- Flufenazine -- 2.2.2 Indole Alkaloids-Induced Parkinsonism -- Reserpine -- Harmaline -- 2.2.3 CNS Stimulants -- Methamphetamine -- 2.2.4 Anti-emetics-Induced Parkinsonism -- Metoclopramide -- 2.3 Others Models of PD -- 2.3.1 Drosophila as a Model of PD -- 2.3.2 Zebrafish as a New Model for PD -- 2.3.3 Encephalitis Virus-Induced PD -- 3 Conclusion -- References -- 4 Animal Models of Huntington’s Disease -- 1 Introduction -- 2 Classification of Animal Models -- 2.1 Toxin Models -- 2.1.1 Energy Metabolism Deficit Models -- 3-Nitropropionic Acid Model -- Malonic Acid Model -- 2.1.2 Excitotoxin Models -- Kainic Acid Model -- Quinolinic Acid Model -- 2.2 Nonhuman Primate Models -- 3 Conclusion -- References -- 5 Animal Models of Epilepsy -- 1 Introduction -- 2 Need of Animal Models -- 2.1 Characteristics of an Ideal Animal Model of Epilepsy -- 2.2 Score -- 3 Classification of Seizure -- 4 Pathophysiology of Seizures -- 5 Classification of Animal Models of Epilepsy (Fig. 3) -- 5.1 Chemical-Induced Convulsions -- 5.1.1 Pentylenetetrazol-Induced Convulsions -- 5.1.2 Bicuculline-Induced Convulsions -- 5.1.3 Strychnine-Induced Convulsions -- 5.1.4 Picrotoxin-Induced Convulsions -- 5.1.5 Kainic Acid-Induced Convulsions -- 5.1.6 Tetanus Toxin-Induced Convulsions -- 5.1.7 Penicillin-Induced Convulsions -- 6 Model of Status Epilepticus -- 6.1 Lithium-Pilocarpine Model of Status Epilepticus -- 6.2 Perforant Path Stimulation Model of Status Epilepticus -- 7 Maximal Electroshock (MES)-Induced Convulsions -- 8 Animal Models of Temporal Lobe Epilepsy -- 8.1 Amygdala Kindling -- 8.2 Hippocampal Kindling -- 8.3 Corneal Kindling -- 8.4 Piriform Cortex .

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