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Topics in biomedical gerontology [electronic resource]

Topics in biomedical gerontology [electronic resource]

자료유형
E-Book(소장)
개인저자
Rath, Pramod C. Sharma, Ramesh. Prasad, S.
서명 / 저자사항
Topics in biomedical gerontology [electronic resource] / Pramod C. Rath, Ramesh Sharma, S. Prasad, editor.
발행사항
Singapore :   Springer,   c2017.  
형태사항
1 online resource (xxi, 355 p.) : ill.
ISBN
9789811021541 9789811021558 (e-book)
일반주기
Title from e-Book title page.  
서지주기
Includes bibliographical references.
이용가능한 다른형태자료
Issued also as a book.  
일반주제명
Geriatrics. Geriatric nursing. Human genetics. Metabolism. Medicine.
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245 0 0 ▼a Topics in biomedical gerontology ▼h [electronic resource] / ▼c Pramod C. Rath, Ramesh Sharma, S. Prasad, editor.
260 ▼a Singapore : ▼b Springer, ▼c c2017.
300 ▼a 1 online resource (xxi, 355 p.) : ▼b ill.
500 ▼a Title from e-Book title page.
504 ▼a Includes bibliographical references.
530 ▼a Issued also as a book.
538 ▼a Mode of access: World Wide Web.
650 0 ▼a Geriatrics.
650 0 ▼a Geriatric nursing.
650 0 ▼a Human genetics.
650 0 ▼a Metabolism.
650 0 ▼a Medicine.
700 1 ▼a Rath, Pramod C.
700 1 ▼a Sharma, Ramesh.
700 1 ▼a Prasad, S.
856 4 0 ▼u https://oca.korea.ac.kr/link.n2s?url=https://doi.org/10.1007/978-981-10-2155-8
945 ▼a KLPA
991 ▼a E-Book(소장)

소장정보

No. 소장처 청구기호 등록번호 도서상태 반납예정일 예약 서비스
No. 1 소장처 중앙도서관/e-Book 컬렉션/ 청구기호 CR 618.97 등록번호 E14014360 도서상태 대출불가(열람가능) 반납예정일 예약 서비스 M

컨텐츠정보

목차

Intro -- Foreword I -- Foreword II -- Preface -- Contents -- Pramod C. Rath -- About the Editors -- Models and Markers in Aging -- 1 Drosophila melanogaster: A Prime Experimental Model System for Aging Studies -- Abstract -- 1 Introduction -- 2 Drosophila melanogaster as a Model Organism for Aging Research -- 3 History of Drosophila Aging Research -- 4 Evaluating Aging in Drosophila: Methods and Approaches -- 4.1 Assessing Life Expectancy -- 4.2 Behavioral Assay -- 4.3 Assessing Aging on the Basis of Dietary Composition -- 4.4 Reproductive Output: Measure to Evaluate Aging -- 4.5 Stress as a Measure to Study Aging -- 4.6 Aging Analysis Utilizing Genetic Approaches -- 5 Contribution of Drosophila in Excavating Molecular and Genetic Mechanisms of Aging -- 5.1 Oxidative Stress -- 5.1.1 Proposed Mechanisms of Oxidative Stress Mediated Aging -- Oxidative Damage to Cellular Components Due to Enhanced Level of ROS -- ROS Mediated Activation of Oxidative Stress Response Signaling Cascades -- 5.2 Molecular Chaperones -- 5.3 Insulin/Insulin-like Growth Factor (IGF)-like Signaling (IIS)/TOR Pathway in Regulation of Longevity and Aging -- 5.4 Dietary Restriction -- 6 Aging and Neurodegeneration -- 7 Concluding Remarks -- Acknowledgments -- References -- 2 Dictyostelium discoideum: A Model System to Study Autophagy Mediated Life Extension -- Abstract -- 1 Introduction -- 2 Model Systems to Study Longevity -- 2.1 Saccharomyces Cerevisiae -- 2.2 Caenorabditis Elegans -- 2.3 Drosophila Melanogaster -- 2.4 Danio Rerio -- 2.5 Rodents -- 2.6 Primates -- 3 Autophagy Promotes Longevity -- 3.1 Genetics Manipulations Leading to Life Extension via Autophagy -- 3.2 Pharmacological Manipulations Affecting Longevity via Autophagy -- 4 Dictyostelium discoideum: A Good Model System to Study Autophagy -- 5 Dictyostelium discoideum: As a Model to Study Longevity -- 6 Sir2D of D. discoideum Promotes Lifespan Extension by Inducing Autophagy -- 7 Conclusions -- Acknowledgments -- References -- 3 Down Regulation of Sirtuins in the Serum of Frail Elderly as Compared to Non-frail Elderly: Promising Diagnostic Protein Marker for Frailty -- Abstract -- 1 Introduction -- 2 Methods -- 2.1 Study Group -- 2.1.1 Evaluation of Serum SIRT1 and SIRT2 by Surface Plasmon Resonance (SPR) -- 3 Results and Discussion -- Acknowledgements -- References -- 4 Morphology of the Human Pancreas During Development and Aging -- Abstract -- 1 Introduction -- 2 Materials and Methods -- 2.1 Specimen Collection -- 2.1.1 Collection of Fetuses -- 2.1.2 Collection of Adult Pancreata -- 2.2 Tissue Preparation -- 2.3 Tissue Processing -- 2.3.1 Hematoxylin and Eosin Staining and Measurements -- 2.3.2 Microtomy and Staining for Light and Transmission Electron Microscopy -- 2.4 Statistical Analysis -- 3 Observations -- 3.1 Macroscopic Anatomy of Developing and Aging Pancreas -- 3.2 Microscopic Anatomy -- 3.2.1 Fetal Pancreas -- 3.2.2 Pancreas of Early Postnatal, Infantile Period and First Decade of Life -- 3.2.3 Secon.

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