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Pathology and biology of human germ cell tumors [electronic resource]

Pathology and biology of human germ cell tumors [electronic resource]

자료유형
E-Book(소장)
개인저자
Nogales, Francisco F. Jimenez, Rafael E.
서명 / 저자사항
Pathology and biology of human germ cell tumors [electronic resource] / Francisco F. Nogales, Rafael E. Jimenez, editors.
발행사항
Berlin :   Springer,   c2017.  
형태사항
1 online resource (xiv, 449 p.) : ill.
ISBN
9783662537732 9783662537756 (e-book)
요약
This book provides, for the first time, a detailed, up-to-date, holistic approach to the pathology and biology of germ cell tumors. The main focus is the complex histopathology of these tumors, but special considerations are also given to their morphologic variations in relation to age, gender and organ. Critical updates are provided on terminology and classification; the discussion of biology and pathogenesis includes references to many molecular genetic and immunohistochemical findings from recent stem cell research. Individual chapters are devoted to germ cell tumors at different anatomic locations, including not only the ovaries and testes but also the mediastinum and central nervous system, and pediatric tumors. All of the contributing authors are opinion leaders from universities of excellence in Europe and the United States. This monograph will be of wide interest to practitioners and researchers in many fields of medicine, including pathology, gynecology, urology, and pediatrics, as well as stem cell scientists.
일반주기
Title from e-Book title page.  
내용주기
Human germ cell tumors. Classifications, definitions and terminology -- Epidemiology of malignant germ cell tumours. The EUROCARE study -- Germ cell tumors from a developmental perspective: cells of origin, pathogenesis and molecular biology. Emerging patterns -- Diagnostic Immunohistochemistry of germ cell tumours -- Clinical management of germ cell tumors -- Germ cell tumors of the female genital tract -- Testicular Germ Cell Tumors -- Mediastinal Germ Cell Tumors -- Central Nervous System Germ Cell Tumors -- Pediatric Germ Cell Tumors -- Germ cell tumors of miscellaneous extra gonadal sites -- Somatic-Type Malignancy in Germ Cell Tumors.
서지주기
Includes bibliographical references and index.
이용가능한 다른형태자료
Issued also as a book.  
일반주제명
Pathology. Gynecology. Urology. Pediatrics. Internal medicine.
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URL
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020 ▼a 9783662537732
020 ▼a 9783662537756 (e-book)
040 ▼a 211009 ▼c 211009 ▼d 211009
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082 0 4 ▼a 616.07 ▼2 23
084 ▼a 616.07 ▼2 DDCK
090 ▼a 616.07
245 0 0 ▼a Pathology and biology of human germ cell tumors ▼h [electronic resource] / ▼c Francisco F. Nogales, Rafael E. Jimenez, editors.
260 ▼a Berlin : ▼b Springer, ▼c c2017.
300 ▼a 1 online resource (xiv, 449 p.) : ▼b ill.
500 ▼a Title from e-Book title page.
504 ▼a Includes bibliographical references and index.
505 0 ▼a Human germ cell tumors. Classifications, definitions and terminology -- Epidemiology of malignant germ cell tumours. The EUROCARE study -- Germ cell tumors from a developmental perspective: cells of origin, pathogenesis and molecular biology. Emerging patterns -- Diagnostic Immunohistochemistry of germ cell tumours -- Clinical management of germ cell tumors -- Germ cell tumors of the female genital tract -- Testicular Germ Cell Tumors -- Mediastinal Germ Cell Tumors -- Central Nervous System Germ Cell Tumors -- Pediatric Germ Cell Tumors -- Germ cell tumors of miscellaneous extra gonadal sites -- Somatic-Type Malignancy in Germ Cell Tumors.
520 ▼a This book provides, for the first time, a detailed, up-to-date, holistic approach to the pathology and biology of germ cell tumors. The main focus is the complex histopathology of these tumors, but special considerations are also given to their morphologic variations in relation to age, gender and organ. Critical updates are provided on terminology and classification; the discussion of biology and pathogenesis includes references to many molecular genetic and immunohistochemical findings from recent stem cell research. Individual chapters are devoted to germ cell tumors at different anatomic locations, including not only the ovaries and testes but also the mediastinum and central nervous system, and pediatric tumors. All of the contributing authors are opinion leaders from universities of excellence in Europe and the United States. This monograph will be of wide interest to practitioners and researchers in many fields of medicine, including pathology, gynecology, urology, and pediatrics, as well as stem cell scientists.
530 ▼a Issued also as a book.
538 ▼a Mode of access: World Wide Web.
650 0 ▼a Pathology.
650 0 ▼a Gynecology.
650 0 ▼a Urology.
650 0 ▼a Pediatrics.
650 0 ▼a Internal medicine.
700 1 ▼a Nogales, Francisco F.
700 1 ▼a Jimenez, Rafael E.
856 4 0 ▼u https://oca.korea.ac.kr/link.n2s?url=https://doi.org/10.1007/978-3-662-53775-6
945 ▼a KLPA
991 ▼a E-Book(소장)

소장정보

No. 소장처 청구기호 등록번호 도서상태 반납예정일 예약 서비스
No. 1 소장처 중앙도서관/e-Book 컬렉션/ 청구기호 CR 616.07 등록번호 E14014197 도서상태 대출불가(열람가능) 반납예정일 예약 서비스 M

컨텐츠정보

목차

Intro -- Preface -- References -- Contents -- Contributors -- 1: Germ Cell Tumors: Classifications, Definitions, and Terminology -- 1.1 Introduction -- 1.2 Classification of Testicular Germ Cell Tumors -- 1.3 Classification of Ovarian Germ Cell Tumors -- 1.4 Definitions and Terminology of Testicular and Ovarian Germ Cell Tumors -- References -- 2: The Epidemiology of Malignant Germ Cell Tumors: The EUROCARE Study -- 2.1 Introduction -- 2.2 Materials -- 2.3 Incidence -- 2.4 Incidence Trends of Gonadal and Extragonadal Germ Cell Tumors -- 2.5 Survival -- References -- 3: Germ Cell Tumors from a Developmental Perspective: Cells of Origin, Pathogenesis, and Molecular Biology (Emerging Patterns) -- 3.1 Introduction -- 3.2 Developmental States of Early Embryonic Cells -- 3.2.1 Restriction Versus Maintaining Developmental Potential -- 3.2.2 OCT4: Key Protein in Pluripotency -- 3.2.3 Specification and Maintenance of the Germline -- 3.2.4 Plasticity of Pluripotent States -- 3.3 Developmental Potential of Germ Cell Tumors -- 3.4 Type 0 GCT -- 3.4.1 Developmental Potential and Incidence -- 3.4.2 Anatomical Distribution -- 3.4.3 Genetics and Pathogenesis -- 3.5 Type I GCT -- 3.5.1 Type I GCT General -- 3.5.1.1 Developmental Potential -- 3.5.1.2 Epidemiology -- 3.5.1.3 Anatomical Distribution -- 3.5.1.4 (Cyto)Genetics -- 3.5.1.5 Epigenetics, including GI -- 3.5.1.6 Animal Models and Pathogenesis -- 3.5.1.7 Summary of the Pathogenesis of Type I GCT -- 3.5.2 Site-Specific Aspects of  Type I GCT -- 3.5.2.1 Sacral Region -- 3.5.2.2 Retroperitoneum -- 3.5.2.3 Stomach -- 3.5.2.4 Mediastinum -- 3.5.2.5 Heart -- 3.5.2.6 Head and Neck -- 3.5.2.7 Brain -- 3.5.2.8 Testis -- 3.5.2.9 Ovary -- 3.5.3 Type I GCT Beyond Infancy -- 3.6 Type II GCT -- 3.6.1 Type II GCT General -- 3.6.1.1 Developmental Potential -- 3.6.1.2 Epidemiology -- 3.6.1.3 Anatomical Distribution -- 3.6.1.4 (Cyto)Genetics -- 3.6.1.5 Epigenetics: Including GI and miRNAs -- 3.6.1.6 Sensitivity/Resistance/Residual Teratoma/Further Progression -- 3.6.1.7 Animal Models and Cell Lines -- 3.6.2 Specific Aspects of Pathogenesis per Anatomical Site -- 3.6.2.1 Dysgenetic Gonad -- 3.6.2.2 Testis -- 3.6.2.3 Ovary -- 3.6.2.4 Mediastinum -- 3.6.2.5 Central Nervous System -- 3.6.3 Type II GCT Before Puberty -- 3.7 Type III GCT -- 3.7.1 Developmental Potential -- 3.7.2 Epidemiology/Risk Factors -- 3.7.3 Anatomical Distribution -- 3.7.4 (Cyto)Genetics -- 3.7.5 Epigenetics Including GI -- 3.7.6 Pathogenesis and Animal Models -- 3.8 Type IV GCT -- 3.8.1 Developmental Potential -- 3.8.2 Epidemiology/Risk Factors -- 3.8.3 Anatomical Distribution -- 3.8.4 (Cyto)Genetics -- 3.8.5 Epigenetics Including GI -- 3.8.6 Pathogenesis and Animal Models -- 3.9 Type V GCT -- 3.9.1 Developmental Potential -- 3.9.2 Epidemiology/Risk Factors -- 3.9.3 Anatomical Distribution -- 3.9.4 (Cyto)Genetics/Epigenetics Including GI -- 3.9.5 Pathogenesis and Animal Models -- 3..

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