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Huntington's disease

Huntington's disease

Material type
단행본
Personal Author
Precious, Sophie V. Rosser, Anne E. Dunnett, S. B. (Stephen B.).
Title Statement
Huntington's disease / edited by Sophie V. Precious, Anne E. Rosser, and Stephen B. Dunnett.
Publication, Distribution, etc
New York :   Humana Press :   Springer,   c2018.  
Physical Medium
xv, 642 p. : ill. (some col.) ; 27 cm.
Series Statement
Methods in molecular biology,1940-6029 ; v. 1780
ISBN
9781493978243 (hbk.) 9781493978250 (ebk.)
Content Notes
Stereological methods to quantify cell loss in the Huntington's Disease human brain / Nasim F. Mehrabi, Malvindar K. Singh-Bains, Henry J. Waldvogel, and Richard L. M. Faull -- Assessing autophagic activity and aggregate formation of mutant huntingtin in mammalian cells / Eleanna Stamatakou, Ye Zhu, and David C. Rubinsztein -- Filter retardation assay facilitates the detection and quantification of heat-stable, amyloidogenic mutant huntingtin aggregates in complex biosamples / Anne Ast, Franziska Schindler, Alexander Buntru, Sigrid Schnoegl, and Erich E. Wanker -- Cellular models : HD patient-derived pluripotent stem cells / Charlene Geater, Sarah Hernandez, Leslie Thompson, and Virginia B. Mattis -- Nonmammalian models of Huntington's Disease / Anjalika Chongtham, Brett Barbaro, Tomas Filip, Adeela Syed, Weijian Huang, Marianne R. Smith, and J. Lawrence Marsh -- Mouse models of Huntington's Disease / Pamela P. Farshim and Gillian P. Bates -- Motor assessment in Huntington's Disease mice / Stephen B. Dunnett and Simon P. Brooks -- Automated operant assessments of Huntington's Disease mouse models / Emma Yhnell and Andreas Heuer -- Neurophysiological assessment of Huntington's Disease model mice / Elissa J. Donzis, Sandra M. Holley, Carlos Cepeda, and Michael S. Levine -- Murine models of Huntington's Disease for evaluating therapeutics / Natalia Kosior and Blair R. Leavitt -- Generating excitotoxic lesion models of Huntington's Disease / Mariah J. Lelos and Stephen B. Dunnett -- Large-brained animal models of Huntington's Disease : sheep / A. Jennifer Morton -- Minipigs as a large-brained animal model for Huntington's Disease : from behavior and imaging to gene therapy / Ralf Reilmann and Verena Schuldenzucker -- Nonhuman primate models of Huntington's Disease and their application in translational research / Romina Aron Badin -- In vivo multidimensional brain imaging in Huntington's Disease animal models / Julien Flament, Philippe Hantraye, and Julien Valette -- Magnetic resonance imaging in Huntington's Disease / Sarah Gregory, Rachael I. Scahill, Geraint Rees, and Sarah Tabrizi -- Biofluid biomarkers in Huntington's Disease / Filipe B. Rodrigues, Lauren M. Byrne, and Edward J. Wild -- Assessing and modulating kynurenine pathway dynamics in Huntington's Disease : focus on kynurenine 3-monooxygenase / Korrapati V. Sathyasaikumar, Carlo Breda, Robert Schwarcz, and Flaviano Giorgini -- Assessing mitochondrial function in in vitro and ex vivo models of Huntington's Disease / I. Luísa Ferreira, Catarina Carmo, Luana Naia, Sandra I. Mota, and A. Cristina Rego -- Using genomic data to find disease-modifying loci in Huntington's Disease (HD) / Peter Holmans and Tim Stone -- CRISPR/Cas9-mediated genome editing for Huntington's Disease / Gabriel Vachey and Nicole Déglon -- Methods for assessing DNA repair and repeat expansion in Huntington's Disease / Thomas Massey, Branduff McAllister, and Lesley Jones -- Translating antisense technology into a treatment for Huntington's Disease / Roger M. Lane, Anne Smith, Tiffany Baumann, Marc Gleichmann, Dan Norris, C. Frank Bennett, and Holly Kordasiewicz -- Disease modification through trophic factor delivery / Mari Savolainen, Dwaine Emerich, and Jeffrey H. Kordower -- Methods to quantify cell signaling and GPCR receptor ligand bias : characterization of drugs that target the endocannabinoid receptors in Huntington's Disease / Amina M. Bagher, Robert B. Laprairie, Melanie E. M. Kelly, and Eileen M. Denovan-Wright -- Dissection and preparation of human primary fetal ganglionic eminence tissue for research and clinical applications / Victoria H. Roberton, Anne E. Rosser, Anne-Marie McGorrian, and Sophie V. Precious -- Robust induction of DARPP32-expressing GABAergic striatal neurons from human pluripotent stem cells / Marija Fjodorova and Meng Li -- Quality assessment and production of human cells for clinical use / Lindsay Fraser, Kevin Bruce, John M. Campbell, and Paul A. De Sousa.
Bibliography, Etc. Note
Includes bibliographical references and index.
Subject Added Entry-Topical Term
Huntington's disease --Laboratory manuals. Huntington Disease.
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001 000045950605
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008 180814s2018 nyua b 001 0 eng d
020 ▼a 9781493978243 (hbk.)
020 ▼a 9781493978250 (ebk.)
035 ▼a (OCoLC)1022085172
040 ▼a YDX ▼b eng ▼e rda ▼c YDX ▼d OCLCF ▼d KUB ▼d 211009
049 ▼a KUBA
050 4 ▼a RC394.H85 ▼b H86 2018
082 0 4 ▼a 616.85/1 ▼2 23
084 ▼a 616.851 ▼2 DDCK
090 ▼a 616.851 ▼b H953
245 0 0 ▼a Huntington's disease / ▼c edited by Sophie V. Precious, Anne E. Rosser, and Stephen B. Dunnett.
260 ▼a New York : ▼b Humana Press : ▼b Springer, ▼c c2018.
300 ▼a xv, 642 p. : ▼b ill. (some col.) ; ▼c 27 cm.
490 1 ▼a Methods in molecular biology, ▼x 1940-6029 ; ▼v v. 1780
490 1 ▼a Springer protocols
504 ▼a Includes bibliographical references and index.
505 0 0 ▼t Stereological methods to quantify cell loss in the Huntington's Disease human brain / ▼r Nasim F. Mehrabi, Malvindar K. Singh-Bains, Henry J. Waldvogel, and Richard L. M. Faull -- ▼t Assessing autophagic activity and aggregate formation of mutant huntingtin in mammalian cells / ▼r Eleanna Stamatakou, Ye Zhu, and David C. Rubinsztein -- ▼t Filter retardation assay facilitates the detection and quantification of heat-stable, amyloidogenic mutant huntingtin aggregates in complex biosamples / ▼r Anne Ast, Franziska Schindler, Alexander Buntru, Sigrid Schnoegl, and Erich E. Wanker -- ▼t Cellular models : HD patient-derived pluripotent stem cells / ▼r Charlene Geater, Sarah Hernandez, Leslie Thompson, and Virginia B. Mattis -- ▼t Nonmammalian models of Huntington's Disease / ▼r Anjalika Chongtham, Brett Barbaro, Tomas Filip, Adeela Syed, Weijian Huang, Marianne R. Smith, and J. Lawrence Marsh -- ▼t Mouse models of Huntington's Disease / ▼r Pamela P. Farshim and Gillian P. Bates -- ▼t Motor assessment in Huntington's Disease mice / ▼r Stephen B. Dunnett and Simon P. Brooks -- ▼t Automated operant assessments of Huntington's Disease mouse models / ▼r Emma Yhnell and Andreas Heuer -- ▼t Neurophysiological assessment of Huntington's Disease model mice / ▼r Elissa J. Donzis, Sandra M. Holley, Carlos Cepeda, and Michael S. Levine -- ▼t Murine models of Huntington's Disease for evaluating therapeutics / ▼r Natalia Kosior and Blair R. Leavitt -- ▼t Generating excitotoxic lesion models of Huntington's Disease / ▼r Mariah J. Lelos and Stephen B. Dunnett -- ▼t Large-brained animal models of Huntington's Disease : sheep / ▼r A. Jennifer Morton -- ▼t Minipigs as a large-brained animal model for Huntington's Disease : from behavior and imaging to gene therapy / ▼r Ralf Reilmann and Verena Schuldenzucker -- ▼t Nonhuman primate models of Huntington's Disease and their application in translational research / ▼r Romina Aron Badin -- ▼t In vivo multidimensional brain imaging in Huntington's Disease animal models / ▼r Julien Flament, Philippe Hantraye, and Julien Valette -- ▼t Magnetic resonance imaging in Huntington's Disease / ▼r Sarah Gregory, Rachael I. Scahill, Geraint Rees, and Sarah Tabrizi -- ▼t Biofluid biomarkers in Huntington's Disease / ▼r Filipe B. Rodrigues, Lauren M. Byrne, and Edward J. Wild -- ▼t Assessing and modulating kynurenine pathway dynamics in Huntington's Disease : focus on kynurenine 3-monooxygenase / ▼r Korrapati V. Sathyasaikumar, Carlo Breda, Robert Schwarcz, and Flaviano Giorgini -- ▼t Assessing mitochondrial function in in vitro and ex vivo models of Huntington's Disease / ▼r I. Luísa Ferreira, Catarina Carmo, Luana Naia, Sandra I. Mota, and A. Cristina Rego -- ▼t Using genomic data to find disease-modifying loci in Huntington's Disease (HD) / ▼r Peter Holmans and Tim Stone -- ▼t CRISPR/Cas9-mediated genome editing for Huntington's Disease / ▼r Gabriel Vachey and Nicole Déglon -- ▼t Methods for assessing DNA repair and repeat expansion in Huntington's Disease / ▼r Thomas Massey, Branduff McAllister, and Lesley Jones -- ▼t Translating antisense technology into a treatment for Huntington's Disease / ▼r Roger M. Lane, Anne Smith, Tiffany Baumann, Marc Gleichmann, Dan Norris, C. Frank Bennett, and Holly Kordasiewicz -- ▼t Disease modification through trophic factor delivery / ▼r Mari Savolainen, Dwaine Emerich, and Jeffrey H. Kordower -- ▼t Methods to quantify cell signaling and GPCR receptor ligand bias : characterization of drugs that target the endocannabinoid receptors in Huntington's Disease / ▼r Amina M. Bagher, Robert B. Laprairie, Melanie E. M. Kelly, and Eileen M. Denovan-Wright -- ▼t Dissection and preparation of human primary fetal ganglionic eminence tissue for research and clinical applications / ▼r Victoria H. Roberton, Anne E. Rosser, Anne-Marie McGorrian, and Sophie V. Precious -- ▼t Robust induction of DARPP32-expressing GABAergic striatal neurons from human pluripotent stem cells / ▼r Marija Fjodorova and Meng Li -- ▼t Quality assessment and production of human cells for clinical use / ▼r Lindsay Fraser, Kevin Bruce, John M. Campbell, and Paul A. De Sousa.
650 0 ▼a Huntington's disease ▼v Laboratory manuals.
650 2 ▼a Huntington Disease.
700 1 ▼a Precious, Sophie V.
700 1 ▼a Rosser, Anne E.
700 1 ▼a Dunnett, S. B. ▼q (Stephen B.).
830 0 ▼a Methods in molecular biology (Clifton, N.J.) ; ▼v v. 1780.
830 0 ▼a Springer protocols.
945 ▼a KLPA

Holdings Information

No. Location Call Number Accession No. Availability Due Date Make a Reservation Service
No. 1 Location Science & Engineering Library/Sci-Info(Stacks2)/ Call Number 616.851 H953 Accession No. 121245601 Availability Available Due Date Make a Reservation Service B M

Contents information

Table of Contents

1. Stereological Methods to Quantify Cell Loss in the Huntington's Disease Human Brain Nasim F. Mehrabi, Malvindar K. Singh-Bains, Henry J. Waldvogel, and Richard L.M. Faull 2. Assessing Autophagic Activity and Aggregate Formation of Mutant Huntingtin in Mammalian Cells Eleanna Stamatakou, Ye Zhu, and David C. Rubinsztein 3. A Filter Retardation Assay Facilitates the Detection and Quantification of Heat-Stable, Amyloidogenic Mutant Huntingtin Aggregates in Complex Biosamples Anne Steinhof, Franziska Schindler, Alexander Buntru, Sigrid Schnoegl, and Erich E. Wanker 4. Cellular Models: HD Patient-Derived Pluripotent Stem Cells Charlene Geater, Sarah Hernandez, Leslie Thompson, and Virginia B. Mattis 5. Non-Mammalian Models of Huntington's Disease Anjalika Chongtham, Brett Barbaro, Tomas Filip, Adeela Syed, Weijian Huang, Marianne R. Smith, and J. Lawrence Marsh 6. Mouse Models of Huntington's Disease Pamela P. Farshim and Gillian P. Bates 7. Motor Assessment in Huntington's Disease Mice Stephen B. Dunnett and Simon P. Brooks 8. Automated Operant Assessments of Huntington's Disease Mouse Models Emma Yhnell and Andreas Heuer 9. Neurophysiological Assessment of Huntington's Disease Model Mice Elissa J. Donzis, Sandra M. Holley, Carlos Cepeda, and Michael S. Levine 10. Murine Models of Huntington's Disease for Evaluating Therapeutics Natalia Kosior and Blair R. Leavitt 11. Generating Excitotoxic Lesion Models of Huntington's Disease Mariah J. Lelos and Stephen B. Dunnett 12. Large-Brained Animal Models of Huntington's Disease: Sheep A. Jennifer Morton 13. Minipigs as Large-Brained Animal Model for Huntington's Disease: From Behavior and Imaging to Gene Therapy Ralf Reilmann and Verena Schuldenzucker 14. Non-Human Primate Models of Huntington's Disease and Their Application in Translational Research Romina Aron Badin 15. In Vivo Multidimensional Brain Imaging in Huntington's Disease Animal Models Julien Flament, Philippe Hantraye, and Julien Valette 16. Magnetic Resonance Imaging in Huntington's Disease Sarah Gregory, Rachael I. Scahill, Geraint Rees, and Sarah Tabrizi 17. Biofluid Biomarkers in Huntington's Disease Filipe B. Rodrigues, Lauren M. Byrne, and Edward J. Wild 18. Assessing and Modulating Kynurenine Pathway Dynamics in Huntington's Disease: Focus on Kynurenine 3-Monooxygenase Korrapati V. Sathyasaikumar, Carlo Breda, Robert Schwarcz, and Flaviano Giorgini 19. Assessing Mitochondrial Function in In Vitro and Ex Vivo Models of Huntington's Disease I. Luisa Ferreira, Catarina Carmo, Luana Naia, Sandra Mota, and A. Cristina Rego 20. Using Genomic Data to Find Disease-Modifying Loci in Huntington's Disease (HD) Peter Holmans and Tim Stone 21. CRISPR/Cas9-Mediated Genome Editing for Huntington's Disease Gabriel Vachey and Nicole Deglon 22. Methods for Assessing DNA Repair and Repeat Expansion in Huntington's Disease Thomas Massey, Branduff McAllister, and Lesley Jones 23. Translating Antisense Technology into a Treatment for Huntington's Disease Roger M. Lane, Anne Smith, Tiffany Baumann, Marc Gleichmann, Dan Norris, C. Frank Bennett, and Holly Kordasiewicz 24. Disease Modification through Trophic Factor Delivery Mari Savolainen, Dwaine Emerich, and Jeffrey H. Kordower 25. Methods to Quantify Cell Signaling and GPCR Receptor Ligand Bias: Characterization of Drugs that Target the Endocannabinoid Receptors in Huntington's Disease Amina M. Bagher, Robert B. Laprairie, Melanie E.M. Kelly, and Eileen M. Denovan-Wright 26. Dissection and Preparation of Human Primary Fetal Ganglionic Eminence Tissue for Research and Clinical Application Victoria H. Roberton, Anne E. Rosser, Anne-Marie McGorrian, and Sophie V. Precious 27. Robust Induction of DARPP32-Expressing GABAergic Striatal Neurons from Human Pl


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