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Acute myeloid leukemia : methods and protocols

Acute myeloid leukemia : methods and protocols

자료유형
단행본
개인저자
Fortina, Paolo.
서명 / 저자사항
Acute myeloid leukemia : methods and protocols / edited by Paolo Fortina ... [et al.].
발행사항
New York, N.Y. :   Humana Press :   Springer,   c2017.  
형태사항
xi, 278 p. : ill. (some col.) ; 27 cm.
총서사항
Methods in molecular biology,1940-6029 ; 1633
ISBN
9781493971404 (print)
요약
This volume describes up-to-date techniques used in understanding the molecular biology of acute myeloid leukemia (AML) and addressing advances in diagnosis, classification, prognostication, and therapeutic strategies to potentially impact overall patient survival. The chapters in this book cover topics such as: cytochemical staining, single-cell mass cytometry of AML and Leukemia stem/progenitor cells, microsphere-based assessment of DNA methylation for AML prognosis, a zebrafish model for evaluating the function of human leukemic gene IDH1 and its mutation, and the isolation of biologically active exosomes from plasma of patients with cancer. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Cutting-edge and practical, Acute Myeloid Leukemia: Methods and Protocols is a valuable resource for scientists and researchers to further their studies and advancements in the field of AML.
내용주기
Molecular malfeasance mediating myeloid malignancies : the genetics of acute myeloid leukemia / Rebecca L. King and Adam Bagg -- Cytochemical staining / Michele E. Paessler, Marybeth Helfrich, and Gerald B.W. Wertheim -- Immunohistochemistry in acute myeloid leukemia / Michael W. Cruise -- Immunophenotyping by multiparameter flow cytometry / Weina Chen and Hung S. Luu -- Single-cell mass cytometry of acute myeloid leukemia and leukemia stem/progenitor cells / Zhihong Zeng, Marina Konopleva, and Michael Andreeff -- Design and application of multiplex PCR seq for the detection of somatic mutations associated with myeloid malignancies / Naomi Park and George Vassiliou -- AMLprofiler : a diagnostic and prognostic microarray for acute myeloid leukemia / Marco Alessandrini, Sharon S. Kappala, and Michael S. Pepper -- Microsphere-based assessment of DNA methylation for AML prognosis / Gerald B.W. Wertheim, Marlise R. Luskin, Martin Carroll, and Stephen R. Master -- Genome-wide analysis of DNA methylation in hematopoietic cells : DNA methylation analysis by WGBS / Mira Jeong, Anna G. Guzman, and Margaret A. Goodell -- Detection and quantification of acute myeloid leukemia-associated fusion transcripts / Jonathan Schumacher, Philippe Szankasi, and Todd W. Kelley -- Targeted next-generation sequencing of acute leukemia / Eric Konnick, Christina M. Lockwood, and David Wu -- Bioinformatics data analysis of next-generation sequencing data from heterogeneous tumor samples / Sean R. Landman and Tae Hyun Hwang -- Zebrafish model for evaluating the function of human leukemic gene IDH1 and its mutation / Alvin C.H. Ma, Xiangguo Shi, Bai-Liang He, Yuhan Guo, and Anskar Y.H. Leung -- Measurement of oncometabolites d-2-hydroxyglutaric acid and l-2-hydroxyglutaric acid / Patricia M. Jones, Richard Boriack, Eduard A. Struys, and Dinesh Rakheja -- Nanofluidic allele-specific digital PCR method for quantifying IDH1 and IDH2 mutation burden in acute myeloid leukemia / Daniel H. Wiseman and Tim C.P. Somervaille -- Isolation of biologically active exosomes from plasma of patients with cancer / Chang-Sook Hong, Sonja Funk, and Theresa L. Whiteside -- Generating and expanding autologous chimeric antigen receptor T cells from patients with acute myeloid leukemia / Saad S. Kenderian, Carl H. June, and Saar Gill.
서지주기
Includes bibliographical references and index.
일반주제명
Acute myeloid leukemia --Laboratory manuals. Leukemia, Myeloid, Acute.
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245 0 0 ▼a Acute myeloid leukemia : ▼b methods and protocols / ▼c edited by Paolo Fortina ... [et al.].
260 ▼a New York, N.Y. : ▼b Humana Press : ▼b Springer, ▼c c2017.
300 ▼a xi, 278 p. : ▼b ill. (some col.) ; ▼c 27 cm.
490 1 ▼a Methods in molecular biology, ▼x 1940-6029 ; ▼v 1633
490 1 ▼a Springer protocols
504 ▼a Includes bibliographical references and index.
505 0 0 ▼t Molecular malfeasance mediating myeloid malignancies : the genetics of acute myeloid leukemia / ▼r Rebecca L. King and Adam Bagg -- ▼t Cytochemical staining / ▼r Michele E. Paessler, Marybeth Helfrich, and Gerald B.W. Wertheim -- ▼t Immunohistochemistry in acute myeloid leukemia / ▼r Michael W. Cruise -- ▼t Immunophenotyping by multiparameter flow cytometry / ▼r Weina Chen and Hung S. Luu -- ▼t Single-cell mass cytometry of acute myeloid leukemia and leukemia stem/progenitor cells / ▼r Zhihong Zeng, Marina Konopleva, and Michael Andreeff -- ▼t Design and application of multiplex PCR seq for the detection of somatic mutations associated with myeloid malignancies / ▼r Naomi Park and George Vassiliou -- ▼t AMLprofiler : a diagnostic and prognostic microarray for acute myeloid leukemia / ▼r Marco Alessandrini, Sharon S. Kappala, and Michael S. Pepper -- ▼t Microsphere-based assessment of DNA methylation for AML prognosis / ▼r Gerald B.W. Wertheim, Marlise R. Luskin, Martin Carroll, and Stephen R. Master -- ▼t Genome-wide analysis of DNA methylation in hematopoietic cells : DNA methylation analysis by WGBS / ▼r Mira Jeong, Anna G. Guzman, and Margaret A. Goodell -- ▼t Detection and quantification of acute myeloid leukemia-associated fusion transcripts / ▼r Jonathan Schumacher, Philippe Szankasi, and Todd W. Kelley -- ▼t Targeted next-generation sequencing of acute leukemia / ▼r Eric Konnick, Christina M. Lockwood, and David Wu -- ▼t Bioinformatics data analysis of next-generation sequencing data from heterogeneous tumor samples / ▼r Sean R. Landman and Tae Hyun Hwang -- ▼t Zebrafish model for evaluating the function of human leukemic gene IDH1 and its mutation / ▼r Alvin C.H. Ma, Xiangguo Shi, Bai-Liang He, Yuhan Guo, and Anskar Y.H. Leung -- ▼t Measurement of oncometabolites d-2-hydroxyglutaric acid and l-2-hydroxyglutaric acid / ▼r Patricia M. Jones, Richard Boriack, Eduard A. Struys, and Dinesh Rakheja -- ▼t Nanofluidic allele-specific digital PCR method for quantifying IDH1 and IDH2 mutation burden in acute myeloid leukemia / ▼r Daniel H. Wiseman and Tim C.P. Somervaille -- ▼t Isolation of biologically active exosomes from plasma of patients with cancer / ▼r Chang-Sook Hong, Sonja Funk, and Theresa L. Whiteside -- ▼t Generating and expanding autologous chimeric antigen receptor T cells from patients with acute myeloid leukemia / ▼r Saad S. Kenderian, Carl H. June, and Saar Gill.
520 ▼a This volume describes up-to-date techniques used in understanding the molecular biology of acute myeloid leukemia (AML) and addressing advances in diagnosis, classification, prognostication, and therapeutic strategies to potentially impact overall patient survival. The chapters in this book cover topics such as: cytochemical staining, single-cell mass cytometry of AML and Leukemia stem/progenitor cells, microsphere-based assessment of DNA methylation for AML prognosis, a zebrafish model for evaluating the function of human leukemic gene IDH1 and its mutation, and the isolation of biologically active exosomes from plasma of patients with cancer. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Cutting-edge and practical, Acute Myeloid Leukemia: Methods and Protocols is a valuable resource for scientists and researchers to further their studies and advancements in the field of AML.
650 0 ▼a Acute myeloid leukemia ▼v Laboratory manuals.
650 2 ▼a Leukemia, Myeloid, Acute.
700 1 ▼a Fortina, Paolo.
830 0 ▼a Springer protocols.
830 0 ▼a Methods in molecular biology (Clifton, N.J.) ; ▼v v. 1633.
945 ▼a KLPA

소장정보

No. 소장처 청구기호 등록번호 도서상태 반납예정일 예약 서비스
No. 1 소장처 과학도서관/Sci-Info(2층서고)/ 청구기호 616.99419 A189 등록번호 121241837 도서상태 대출가능 반납예정일 예약 서비스 B M

컨텐츠정보

목차

Molecular Malfeasance Mediating Myeloid Malignancies: The Genetics of Acute Myeloid Leukemia
Cytochemical Staining
Immunohistochemistry in Acute Myeloid Leukemia
Immunophenotyping by Multiparameter Flow Cytometry
Single-Cell Mass Cytometry of Acute Myeloid Leukemia and Leukemia Stem/Progenitor Cells
Design and Application of Multiplex-PCR-Seq for the Detection of Somatic Mutations Associated with Myeloid Malignancies
AMLProfiler: A Diagnostic and Prognostic Microarray for Acute Myeloid Leukemia
Microsphere-Based Assessment of DNA Methylation for AML Prognosis
Genome-Wide Analysis of DNA Methylation in Hematopoietic Cells: DNA Methylation Analysis by WGBS
Detection and Quantification of Acute Myeloid Leukemia-Associated Fusion Transcripts
Targeted Next-Generation Sequencing of Acute Leukemia
Bioinformatics Data Analysis of Next-Generation Sequencing Data from Heterogeneous Tumor Samples
A Zebrafish Model for Evaluating the Function of Human Leukemic Gene IDH1 and its Mutation
Measurement of Oncometabolites D-2-Hydroxyglutaric Acid and L-2-Hydroxyglutaric Acid
Nanofluidic Allele-Specific Digital PCR Method for Quantifying IDH1 and IDH2 Mutation Burden in Acute Myeloid Leukaemia
Isolation of Biologically Active Exosomes from Plasma of Patients with Cancer
Generating and Expanding Autologous Chimeric Antigen Receptor T Cells from Patients with Acute Myeloid Leukemia.

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