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Molecular diagnostics for melanoma : methods and protocols

Molecular diagnostics for melanoma : methods and protocols

Material type
단행본
Personal Author
Thurin, Magdalena. Marincola, Francesco M..
Title Statement
Molecular diagnostics for melanoma : methods and protocols / edited by Magdalena Thurin, Francesco M. Marincola.
Publication, Distribution, etc
New York :   Humana Press :   Springer,   2014.  
Physical Medium
xxiii, 712 p. : ill. (some col.) ; 27 cm.
Series Statement
Methods in Molecular Biology,1064-3745 ; 1102
ISBN
9781627037266 9781627037273 (electronic bk.) 1627037276 (electronic bk.)
요약
In Molecular Diagnostics for Melanoma: Methods and Protocols, expert researchers and clinicians in the field of melanoma provide updated information on biomarkers and assays for diagnosis, prognosis, and assays predicting response to treatment for routine testing. The focus of the volume is on biomarkers with established clinical validity rather than those on early discovery stage. With additional in-depth discussion of the molecular biology and pathology of melanoma, treatment options in adjuvant and metastatic setting, and implications of biomarker testing for clinical management of melanoma patients. Written in the highly successful Methods in Molecular Biology series format, chapters include extensive introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and key tips on troubleshooting and avoiding known pitfalls. Comprehensive and practical, Molecular Diagnostics for Melanoma: Methods and Protocols seeks to provide both clinicians and scientists with technical information and extensive background information on the wide ranging approaches available in the field of diagnostics of melanoma.
Content Notes
Novel Insights/translational Implication from the Emerging Biology of Melanoma -- Emerging Clinical Issues in Melanoma in the Molecularly Targeted Era -- Integrating Molecular Biomarkers Into Current Clinical Management In Melanoma -- Advances in Adjuvant Therapy: Potential for Prognostic and Predictive Biomarkers -- Immunologic Monitoring of Cancer Vaccine Trials Using the ELISPOT Assay -- Markers for Anti-Cytotoxic T-lymphocyte Antigen 4 (CTLA-4) Therapy in Melanoma -- Marker Utility for Combination Therapy -- Assaying for BRAF V600E in Tissue and Blood in Melanoma -- Selecting Patients for KIT Inhibition in Melanoma -- Detecting Mechanisms of Acquired BRAF inhibitor Resistance in Melanoma -- Current Status of Diagnostic and Prognostic Markers in Melanoma -- Chromosomal Copy Number Analysis in Melanoma Diagnostics -- Construction and Analysis of Multi-Parameter Prognostic Models for Melanoma Outcome -- Immunohistochemical Diagnostic and Prognostic Markers for Melanoma -- Lymphatic Invasion as a Prognostic Biomarker in Primary Cutaneous Melanoma -- Tumor Infiltrating Lymphocytes and Their Significance in Melanoma Prognosis -- Pathological Staging of Melanoma -- Genotyping of Human Leukocyte Antigen (HLA) Ancestral Haplotypes as Prognostic Marker in Cancer Using PCR Analysis -- B7-H Abnormalities in Melanoma and Clinical Relevance -- Melanoma Susceptibility Genes and Risk Assessment -- Clinical, Pathologic, and Imaging Features, and Biological Markers of Uveal Melanoma -- A Prognostic Test to Predict Risk of Metastasis in Uveal Melanoma Based on a 15-Gene Expression Profile -- Molecular Karyotyping for Detection of Prognostic Markers in Fine Needle Aspirate Biopsy Samples of Uveal Melanoma -- ERBB4 Mutation Analysis: Emerging Molecular Target for Melanoma Treatment -- Epigenetic Markers of Prognosis in Melanoma -- Isolation of Melanoma Cell Subpopulations Using Negative Selection -- Circulating Tumor Cells as Prognostic Biomarkers in Cutaneous Melanoma Patients -- Detection of Chondroitin Sulfate Proteoglycan 4 (CSPG4) in Melanoma -- Targeting Damage Associated Molecular Pattern Molecules (DAMPs) and DAMP Receptors in Melanoma -- The Clinical Use of PET/CT in the Evaluation of Melanoma -- Immune System Functional Pathway Analysis Using Single Cell Network Profiling (SCNP): A Novel Tool in Cancer Immunotherapy -- Quantitative and Spatial Image Analysis of Tumor and Draining Lymph Nodes Using Immunohistochemistry and High Resolution Multispectral Imaging to Predict Metastasis -- COLD-PCR Enriches Low-Level Variant DNA Sequences and Increases the Sensitivity of Genetic Testing -- Isolation of Circulating MicroRNAs from Microvesicles found in Human Plasma -- Detection of Circulating Tumor Cells by Photoacustic Flowmetry -- Statistical Design and Evaluation of Biomarker Studies -- Tissue Resources for Clinical Use and Marker Studies in Melanoma.
Bibliography, Etc. Note
Includes bibliographical references and index.
Subject Added Entry-Topical Term
Melanoma -- Molecular diagnosis -- Laboratory manuals.
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020 ▼a 9781627037273 (electronic bk.)
020 ▼a 1627037276 (electronic bk.)
035 ▼a (OCoLC)868585814
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082 0 4 ▼a 616.99477 ▼2 23
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090 ▼a 616.99477 ▼b M718
245 0 0 ▼a Molecular diagnostics for melanoma : ▼b methods and protocols / ▼c edited by Magdalena Thurin, Francesco M. Marincola.
260 ▼a New York : ▼b Humana Press : ▼b Springer, ▼c 2014.
300 ▼a xxiii, 712 p. : ▼b ill. (some col.) ; ▼c 27 cm.
490 1 ▼a Methods in Molecular Biology, ▼x 1064-3745 ; ▼v 1102
490 1 ▼a Springer protocols
504 ▼a Includes bibliographical references and index.
505 0 0 ▼t Novel Insights/translational Implication from the Emerging Biology of Melanoma -- ▼t Emerging Clinical Issues in Melanoma in the Molecularly Targeted Era -- ▼t Integrating Molecular Biomarkers Into Current Clinical Management In Melanoma -- ▼t Advances in Adjuvant Therapy: Potential for Prognostic and Predictive Biomarkers -- ▼t Immunologic Monitoring of Cancer Vaccine Trials Using the ELISPOT Assay -- ▼t Markers for Anti-Cytotoxic T-lymphocyte Antigen 4 (CTLA-4) Therapy in Melanoma -- ▼t Marker Utility for Combination Therapy -- ▼t Assaying for BRAF V600E in Tissue and Blood in Melanoma -- ▼t Selecting Patients for KIT Inhibition in Melanoma -- ▼t Detecting Mechanisms of Acquired BRAF inhibitor Resistance in Melanoma -- ▼t Current Status of Diagnostic and Prognostic Markers in Melanoma -- ▼t Chromosomal Copy Number Analysis in Melanoma Diagnostics -- ▼t Construction and Analysis of Multi-Parameter Prognostic Models for Melanoma Outcome -- ▼t Immunohistochemical Diagnostic and Prognostic Markers for Melanoma -- ▼t Lymphatic Invasion as a Prognostic Biomarker in Primary Cutaneous Melanoma -- ▼t Tumor Infiltrating Lymphocytes and Their Significance in Melanoma Prognosis -- ▼t Pathological Staging of Melanoma -- ▼t Genotyping of Human Leukocyte Antigen (HLA) Ancestral Haplotypes as Prognostic Marker in Cancer Using PCR Analysis -- ▼t B7-H Abnormalities in Melanoma and Clinical Relevance -- ▼t Melanoma Susceptibility Genes and Risk Assessment -- ▼t Clinical, Pathologic, and Imaging Features, and Biological Markers of Uveal Melanoma -- ▼t A Prognostic Test to Predict Risk of Metastasis in Uveal Melanoma Based on a 15-Gene Expression Profile -- ▼t Molecular Karyotyping for Detection of Prognostic Markers in Fine Needle Aspirate Biopsy Samples of Uveal Melanoma -- ▼t ERBB4 Mutation Analysis: Emerging Molecular Target for Melanoma Treatment -- ▼t Epigenetic Markers of Prognosis in Melanoma -- Isolation of Melanoma Cell Subpopulations Using Negative Selection -- ▼t Circulating Tumor Cells as Prognostic Biomarkers in Cutaneous Melanoma Patients -- ▼t Detection of Chondroitin Sulfate Proteoglycan 4 (CSPG4) in Melanoma -- ▼t Targeting Damage Associated Molecular Pattern Molecules (DAMPs) and DAMP Receptors in Melanoma -- ▼t The Clinical Use of PET/CT in the Evaluation of Melanoma -- ▼t Immune System Functional Pathway Analysis Using Single Cell Network Profiling (SCNP): A Novel Tool in Cancer Immunotherapy -- ▼t Quantitative and Spatial Image Analysis of Tumor and Draining Lymph Nodes Using Immunohistochemistry and High Resolution Multispectral Imaging to Predict Metastasis -- ▼t COLD-PCR Enriches Low-Level Variant DNA Sequences and Increases the Sensitivity of Genetic Testing -- ▼t Isolation of Circulating MicroRNAs from Microvesicles found in Human Plasma -- ▼t Detection of Circulating Tumor Cells by Photoacustic Flowmetry -- ▼t Statistical Design and Evaluation of Biomarker Studies -- ▼t Tissue Resources for Clinical Use and Marker Studies in Melanoma.
520 ▼a In Molecular Diagnostics for Melanoma: Methods and Protocols, expert researchers and clinicians in the field of melanoma provide updated information on biomarkers and assays for diagnosis, prognosis, and assays predicting response to treatment for routine testing. The focus of the volume is on biomarkers with established clinical validity rather than those on early discovery stage. With additional in-depth discussion of the molecular biology and pathology of melanoma, treatment options in adjuvant and metastatic setting, and implications of biomarker testing for clinical management of melanoma patients. Written in the highly successful Methods in Molecular Biology series format, chapters include extensive introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and key tips on troubleshooting and avoiding known pitfalls. Comprehensive and practical, Molecular Diagnostics for Melanoma: Methods and Protocols seeks to provide both clinicians and scientists with technical information and extensive background information on the wide ranging approaches available in the field of diagnostics of melanoma.
650 0 ▼a Melanoma ▼x Molecular diagnosis ▼v Laboratory manuals.
700 1 ▼a Thurin, Magdalena.
700 1 ▼a Marincola, Francesco M..
740 0 2 ▼a Prognostic Test to Predict Risk of Metastasis in Uveal Melanoma Based on a 15-Gene Expression Profile.
740 0 2 ▼a Clinical Use of PET/CT in the Evaluation of Melanoma.
830 0 ▼a Methods in molecular biology (Clifton, N.J.) ; ▼v v. 1102.
830 0 ▼a Springer protocols (Series)
945 ▼a KLPA

Holdings Information

No. Location Call Number Accession No. Availability Due Date Make a Reservation Service
No. 1 Location Science & Engineering Library/Sci-Info(Stacks2)/ Call Number 616.99477 M718 Accession No. 121228413 Availability Available Due Date Make a Reservation Service B M

Contents information

Table of Contents

Part I. Clinical Challenges and Current Status of Treatment of Melanoma 1. Novel Insights/translational Implication from the Emerging Biology of Melanoma Antoni Ribas 2. Emerging Clinical Issues in Melanoma in the Molecularly Targeted Era Ryan J. Sullivan and Michael B. Atkins 3. Integrating Molecular Biomarkers Into Current Clinical Management In Melanoma Ragini Kudchadkar, Geoffrey Gibney, and Vernon K. Sondak Part II. Biomarkers for Prediction of Response and Resistance to Treatment 4. Advances in Adjuvant Therapy: Potential for Prognostic and Predictive Biomarkers Diwakar Davar, Ahmad A. Tarhini, Helen Gogas, and John M. Kirkwood 5. Immunologic Monitoring of Cancer Vaccine Trials Using the ELISPOT Assay Lisa H. Butterfield and Mary Jo Buffo 6. Markers for Anti-Cytotoxic T-lymphocyte Antigen 4 (CTLA-4) Therapy in Melanoma Michael A. Postow, Jianda Yuan, Shigehisa Kitano, Alexander M. Lesokhin, and Jedd D. Wolchok 7. Marker Utility for Combination Therapy Ester Simeone, Antonio M. Grimaldi, and Paolo A. Ascierto 8. Assaying for BRAF V600E in Tissue and Blood in Melanoma David J. Panka, James W. Mier, and Ryan J. Sullivan 9. Selecting Patients for KIT Inhibition in Melanoma Richard D. Carvajal, Omid Hamid, and Cristina R. Antonescu 10. Detecting Mechanisms of Acquired BRAF inhibitor Resistance in Melanoma Roger Lo and Hubing Shi 11. Current Status of Diagnostic and Prognostic Markers in Melanoma Danielle Levine and David E. Fisher 12. Chromosomal Copy Number Analysis in Melanoma Diagnostics Jeffrey P. North, Swapna Vemula, and Boris C. Bastian 13. Construction and Analysis of Multi-Parameter Prognostic Models for Melanoma Outcome Bonnie E. Gould Rothberg and David L. Rimm 14. Immunohistochemical Diagnostic and Prognostic Markers for Melanoma Mehdi Nosrati and Mohammed Kashani-Sabet 15. Lymphatic Invasion as a Prognostic Biomarker in Primary Cutaneous Melanoma Xiaowei Xu, Phyllis A. Gimotty, DuPont Guerry, Giorgos Karakousis, and David E. Elder 16. Tumor Infiltrating Lymphocytes and Their Significance in Melanoma Prognosis Tobias Schatton, Richard A. Scolyer, John F. Thompson, and Martin C. Mihm, Jr. 17. Pathological Staging of Melanoma David E. Elder 18. Genotyping of Human Leukocyte Antigen (HLA) Ancestral Haplotypes as Prognostic Marker in Cancer Using PCR Analysis Lisa Villabona, Emilia Andersson, Maddalena Marchesi, and Giuseppe V. Masucci 19. B7-H Abnormalities in Melanoma and Clinical Relevance Barbara Seliger 20. Melanoma Susceptibility Genes and Risk Assessment Alexander Marxuka-Alcala, Michele Jacobs Gabree, and Hensin Tsao Part IV. Uveal Melanoma 21. Clinical, Pathologic, and Imaging Features, and Biological Markers of Uveal Melanoma Hans E. Grossniklaus and Alia B. Rashid 22. A Prognostic Test to Predict Risk of Metastasis in Uveal Melanoma Based on a 15-Gene Expression Profile J. William Harbour 23. Molecular Karyotyping for Detection of Prognostic Markers in Fine Needle Aspirate Biopsy Samples of Uveal Melanoma Arupa Ganguly, Jennifer Richards-Yutz, and Kathryn G. Ewens Part V. Emerging Markers/Targets in Melanoma 24. ERBB4 Mutation Analysis: Emerging Molecular Target for Melanoma Treatment Christopher Lau, Keith J. Killian, Yardena Samuels, and Udo Rudloff 25. Epigenetic Markers of Prognosis in Melanoma Luca Sigalotti, Elisabetta Fratta, Giulia Parisi, Sandra Coral, and Michele Maio 26. Isolation of Melanoma Cell Subpopulations Using Negative Selection Ana Slipicevic, Rajasekharan Somasundaram, Katrin Sproesser, and Meenhard Herlyn 27. Circulating Tumor Cells as Prognostic Biomarkers in Cutaneous Melanoma Patients Eiji Kiyohara, Keisuke Hata, Stella Lam, and Dave S. B. Hoon 28. Detection of Chondroitin Sulfate Proteoglycan 4 (CSPG4) in Melanoma Yangyang Wang, Francesco Sabbatino, Xinhui Wang, and Soldano Ferrone 29. Targeting Damage A


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