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Crystals, X-rays, and proteins : comprehensive protein crystallography

Crystals, X-rays, and proteins : comprehensive protein crystallography

자료유형
단행본
서명 / 저자사항
Crystals, X-rays, and proteins : comprehensive protein crystallography / Dennis Sherwood, Jon Cooper.
발행사항
New York : Oxford University Press, 2011.
형태사항
xvii 621 p. : ill. ; 26 cm.
ISBN
9780199559046 (hbk. : alk. paper)
요약
"A complete account of the theory of the diffraction of x-rays by crystals with particular reference to the processes of determining the structures of protein molecules, this book is aimed primarily at structural biologists and biochemists but will also be valuable to those entering the field with a background in physical sciences or chemistry. It may be used at any post-school level, and develops from first principles all relevant mathematics, diffraction and wave theory, assuming no mathematical knowledge beyond integral calculus. The book covers a host of important topics in the area, including:- The practical aspects of sample preparation and x-ray data collection, using both laboratory and synchrotron sources - Data analysis at both theoretical and practical levels- The important role played by the Patterson function in structure analysis by both molecular replacement and experimental phasing approaches - Methods for improving the resulting electron density map - The theoretical basis of methods used in refinement of protein crystal structures - In-depth explanation of the crucial task of defining the binding sites of ligands and drug molecules - The complementary roles of other diffraction methods which reveal further detail of great functional importance in a crystal structure"--Provided by publisher.
일반주기
Update to: Crystals, X-rays, and proteins / Dennis Sherwood. 1976.
내용주기
Machine generated contents note: -- 1. The crystalline state and its study2. Vector analysis and complex algebra3. Crystal systematics4. Waves and electromagnetic radiation5. Fourier transforms and convolutions6. Diffraction7. Diffraction from one-dimensional obstacles8. Diffraction from a three-dimensional lattice9. The contents of the unit cell10. Experimental methods: sample preparatio11. Experimental techniques: data collection and analysis12. The Phase problem and the Patterson function13. Molecular replacement14. Solving the phase problem experimentally15. Refinement16. Complementary crystallographic methods.
서지주기
Includes bibliographical references and index.
일반주제명
Proteins -- Structure. X-ray crystallography. Proteins -- chemistry. Crystallography, X-Ray -- methods. Protein Conformation.
000 03205camuu2200361 a 4500
001 000045632874
005 20110303110956
008 110302s2011 nyua b 001 0 eng d
010 ▼a 2010032106
020 ▼a 9780199559046 (hbk. : alk. paper)
035 ▼a (KERIS)REF000016006856
040 ▼a DNLM/DLC ▼c DLC ▼d 211009
050 0 0 ▼a QP551 ▼b .S535 2011
082 0 0 ▼a 612.8 ▼2 22
084 ▼a 612.8 ▼2 DDCK
090 ▼a 612.8 ▼b S554c
100 1 ▼a Sherwood, Dennis.
245 1 0 ▼a Crystals, X-rays, and proteins : ▼b comprehensive protein crystallography / ▼c Dennis Sherwood, Jon Cooper.
260 ▼a New York : ▼b Oxford University Press, ▼c 2011.
300 ▼a xvii 621 p. : ▼b ill. ; ▼c 26 cm.
500 ▼a Update to: Crystals, X-rays, and proteins / Dennis Sherwood. 1976.
504 ▼a Includes bibliographical references and index.
505 8 ▼a Machine generated contents note: -- 1. The crystalline state and its study2. Vector analysis and complex algebra3. Crystal systematics4. Waves and electromagnetic radiation5. Fourier transforms and convolutions6. Diffraction7. Diffraction from one-dimensional obstacles8. Diffraction from a three-dimensional lattice9. The contents of the unit cell10. Experimental methods: sample preparatio11. Experimental techniques: data collection and analysis12. The Phase problem and the Patterson function13. Molecular replacement14. Solving the phase problem experimentally15. Refinement16. Complementary crystallographic methods.
520 ▼a "A complete account of the theory of the diffraction of x-rays by crystals with particular reference to the processes of determining the structures of protein molecules, this book is aimed primarily at structural biologists and biochemists but will also be valuable to those entering the field with a background in physical sciences or chemistry. It may be used at any post-school level, and develops from first principles all relevant mathematics, diffraction and wave theory, assuming no mathematical knowledge beyond integral calculus. The book covers a host of important topics in the area, including:- The practical aspects of sample preparation and x-ray data collection, using both laboratory and synchrotron sources - Data analysis at both theoretical and practical levels- The important role played by the Patterson function in structure analysis by both molecular replacement and experimental phasing approaches - Methods for improving the resulting electron density map - The theoretical basis of methods used in refinement of protein crystal structures - In-depth explanation of the crucial task of defining the binding sites of ligands and drug molecules - The complementary roles of other diffraction methods which reveal further detail of great functional importance in a crystal structure"--Provided by publisher.
650 0 ▼a Proteins ▼x Structure.
650 0 ▼a X-ray crystallography.
650 1 2 ▼a Proteins ▼x chemistry.
650 2 2 ▼a Crystallography, X-Ray ▼x methods.
650 2 2 ▼a Protein Conformation.
700 1 ▼a Cooper, Jon ▼q (Jonathan B.)
700 1 ▼a Sherwood, Dennis. ▼t Crystals, X-rays, and proteins.
945 ▼a KLPA

소장정보

No. 소장처 청구기호 등록번호 도서상태 반납예정일 예약 서비스
No. 1 소장처 과학도서관/단행본실(2층)/ 청구기호 612.8 S554c 등록번호 121206323 도서상태 대출가능 반납예정일 예약 서비스 B M

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