CONTENTS
PART ONE Normal Sleep = 1
SECTION I Normal Sleep and Its Variations / MARY A. CARSKADON ; THOMAS ROTH = 3
CHAPTER 1 History of Sleep Physiology and Medicine / WILLIAM C. DEMENT = 3
CHAPTER 2 Normal Human Sleep: An Overview / MARY A. CARSKADON ; WILLIAM C. DEMENT = 16
CHAPTER 3 Normal Aging / DONALD L. BLIWISE = 26
CHAPTER 4 Daytime Sleepiness and Alertness / THOMAS ROTH ; TIMOTHY A. ROEHRS ; MARY A. CARSKADON ; WILLIAM C. DEMENT = 40
CHAPTER 5 Sleep Deprivation / MICHAEL H. BONNET = 50
SECTION II Phylogeny / ALLAN RECHTSCHAFFEN = 69
CHAPTER 6 Mammalian Sleep / HAROLD ZEPELIN = 69
CHAPTER 7 Avian Sleep / CHARLES J. AMLANER, JR. ; NIGEL J. BALL = 81
CHAPTER 8 Sleep in Insects and Nonmammalian Vertebrates / KRISTYNA M. HARTSE = 95
SECTION III Sleep Mechanisms / MICHAEL H. CHASE = 105
CHAPTER 9 Brain Electrical Activity and Sensory Processing During Waking and Sleep Stales / M. STERIADE = 105
CHAPTER 10 Brainstem Mechanisms Generating REM Sleep / J. M. SIEGEL = 125
CHAPTER 11 Basic Mechanisms of Sleep-Wake States / BARBARA E. JONES = 145
CHAPTER 12 The Control of Motoneurons During Sleep / MICHAEL H. CHASE ; FRANCISCO R. MORALES = 163
SECTION IV Physiology in Sleep / MEIR H. KRYGER = 177
CHAPTER 13 Respiratory Neurons and Sleep / JOHN OREM = 177
CHAPTER 14 The Autonomic Nervous System in Sleep / PIER LUIGI PARMEGGIANI = 194
CHAPTER 15 Control of Ventilation During Sleep / NEIL J. DOUGLAS = 204
CHAPTER 16 Breathing During Sleep in Normal Subjects / JEAN KRIEGER = 212
CHAPTER 17 Sleep at High Altitudes / JOHN V. WEIL = 224
CHAPTER 18 Higher Cerebral Regulation of Cardiovascular and Respiratory Functions / JAMES E. SKINNER ; MARK MOLNAR ; RONALD M. HARPER = 231
CHAPTER 19 Gastrointestinal Physiology / WILLIAM C. ORR = 252
CHAPTER 20 Temperature Regulation / STEVEN F. GLOTZBACH ; H. CRAIG HELLER = 260
SECTION V Chronobiology / G. RICHARDSON = 277
CHAPTER 21 Circadian Rhythms in Mammals: Formal Properties and Environmental Influences / RALPH E. MISTLBERGER ; BENJAMIN RUSAK = 277
CHAPTER 22 Anatomy and Physiology of the Mammalian Circadian System / MARY E. HARRINGTON ; BENJAMIN RUSAK ; RALPH E. MISTLBERGER = 286
CHAPTER 23 Circadian Rhythms in Humans: An Overview / MEIR H. KRYGER ; THOMAS ROTH ; MARY CARSKADON = 301
CHAPTER 24 Sleep Homeostasis and Models of Sleep Regulation / ALEXANDER A. BORBELY = 309
CHAPTER 25 Circadian Rhythms in Subjective Activation, Mood, and Performance Efficiency / TIMOTHY H. MONK = 321
SECTION VI Pharmacology / ANTHONY N. NICHOLSON = 331
CHAPTER 26 Pharmacology of Sleep and Wakefulness: An Introduction / ANTHONY N. NICHOLSON = 331
CHAPTER 27 Neurotransmission and Receptor Pharmacology / J.-M. GAILLARD = 333
CHAPTER 28 Neurotransmitter Systems / J.-M. GAILLARD ; ANTHONY N. NICHOLSON ; PETA A. PASCOE = 338
CHAPTER 29 Benzodiazepines and GABA-ergic Transmission / J.-M. GAILLARD = 349
CHAPTER 30 Hypnotics: Clinical Pharmacology and Therapeutics / ANTHONY N. NICHOLSON = 355
CHAPTER 31 Medications: Effect on Sleep and Wakefulness / ANTHONY N. NICHOLSON ; CATHERINE M. BRADLEY ; PETA A. PASCOE = 364
SECTION VII Psychobiology and Dreaming / ERNEST HARTMANN = 373
CHAPTER 32 Dreams and the Biology of Sleep / ROBERT W. McCARLEY = 373
CHAPTER 33 The Psychophysiology of Dreams / R. T. PIVIK = 384
CHAPTER 34 The Scientific Study of Dreaming / MILTON KRAMER = 394
CHAPTER 35 Dreams and Their Meaning / ROSALIND D. CARTWRIGHT = 400
CHAPTER 36 Nightmares and Other Dreams / ERNEST HARTMANN = 407
PART TWO Abnormal Sleep = 411
SECTION VIII Impact, Presentation, and Diagnosis / MICHAEL S. ALDRICH = 413
CHAPTER 37 Approach to the Patient with Disordered Sleep / MICHAEL W. NAYLOR ; MICHAEL S. ALDRICH = 413
CHAPTER 38 Cardinal Manifestations of Sleep Disorders / MICHAEL S. ALDRICH = 413
CHAPTER 39 Classification of Sleep Disorders / MICHAEL J. THORPY = 426
CHAPTER 40 Epidemiology of Sleep Disorders / MARKKU PARTINEN = 437
CHAPTER 41 Sleep Medicine, Public Policy, and Public Health / MERRILL M. MITLER ; DAVID F. DINGES ; WILLIAM C. DEMENT = 453
SECTION IX Disorders of Chronobiology / GARY RICHARDSON = 463
CHAPTER 42 Jet Lag and Sleep Disruption / R. CURTIS GRAEBER = 463
CHAPTER 43 Shift Work / TIMOTHY H. MONK = 471
CHAPTER 44 Chronic Insomnias Associated with Circadian Rhythm Disorders / TIMOTHY ROEHRS ; THOMAS ROTH = 477
SECTION X Insomnia / FRANK ZORICK = 483
CHAPTER 45 Overview of Insomnia / FRANK ZORICK = 483
CHAPTER 46 Transient and Short-Term Insomnia / TIMOTHY ROEHRS ; FRANK ZORICK ; THOMAS ROTH = 486
CHAPTER 47 Primary Insomnia / PETER HAURI = 494
CHAPTER 48 Insomnia in Adult Psychiatric Disorders / JAMES K. WALSH ; KENNETH L. MOSS ; JEFFERY SUGARMAN = 500
CHAPTER 49 Medical Causes of Insomnia / VIRGIL WOOTEN = 509
CHAPTER 50 Insomnia Associated with Specific Polysomnographic Findings / PAUL A. FREDRICKSON ; BRUCE R. KRUEGER = 523
CHAPTER 51 Behavioral Therapy for Insomnia / EDWARD J. STEPANSKI = 535
CHAPTER 52 Sleep Hygiene / VINCENT P. ZARCONE, JR. = 542
CHAPTER 53 Fatal Familial Insomnia: A New Prion Disease / E. LUGARESI ; P. MONTAGNA = 547
SECTION XI Primary Disorders of Daytime Somnolence / CHRISTIAN GUILLEMINAULT = 549
CHAPTER 54 Narcolepsy Syndrome / CHRISTIAN GUILLEMINAULT = 549
CHAPTER 55 Idiopathic Central Nervous System Hypersomnia / CHRISTIAN GUILLEMINAULT = 562
SECTION XII Parasomnias / CHRISTIAN GUILLEMINAULT = 567
CHAPTER 56 Sleep Terrors and Sleepwalking / S. PRICE KEEFAUVER ; CHRISTIAN GUILLEMINAULT = 567
CHAPTER 57 REM Sleep Behavior Disorder / MARK W. MAHOWALD ; CARLOS H. SCHENCK = 574
CHAPTER 58 Restless Legs Syndrome and Periodic Limb Movements During Sleep / JACQUES MONTPLAISIR ; ROGER GODBOUT ; GILLES PELLETIER ; HECTOR WARNES = 589
CHAPTER 59 Bruxism / ERNEST HARTMANN = 598
SECTION XIII Sleep Breathing Disorders / MEIR H. KRYGER = 603
CHAPTER 60 Drugs and Sleep Respiration / RICHARD W. ROBINSON ; CLIFFORD W. ZWILLICH = 603
CHAPTER 61 Snoring: Pathogenic, Clinical, and Therapeutic Aspects / E. LUGARESI ; F. CIRIGNOTTA ; P. MONTAGNA ; E. SFORZA = 621
CHAPTER 62 Central Sleep Apnea / DAVID P. WHITE = 630
CHAPTER 63 Anatomy and Physiology of Upper Airway Obstruction / SHIROH ISONO ; JOHN E. REMMERS = 642
CHAPTER 64 Cardiorespiratory Changes in Obstructive Sleep Apnea / JOHN W. SHEPARD, JR. = 657
CHAPTER 65 Clinical Features and Evaluation of Obstructive Sleep Apnea / CHRISTIAN GUILLEMINAULT = 667
CHAPTER 66 Medical Therapy for Sleep Apnea / MARK H. SANDERS = 678
CHAPTER 67 Continuous Positive Airway Pressure in Sleep-Disordered Breathing / COLIN E. SULLIVAN ; RONALD R. GRUNSTEIN = 694
CHAPTER 68 Surgical Therapy for Obstructive Sleep Apnea / NELSON B. POWELL ; CHRISTIAN GUILLEMINAULT ; ROBERT W. RILEY = 706
CHAPTER 69 Dental Appliances for the Treatment of Snoring and Obstructive Sleep Apnea / ALAN A. LOWE = 772
CHAPTER 70 Management of Obstructive Sleep Apnea: Overview / MEIR H. KRYGER = 736
CHAPTER 71 Asthma / NEIL J. DOUGLAS = 748
CHAPTER 72 Breathing During Sleep in Patients with Chronic Obstructive Pulmonary Disease / NEIL J. DOUGLAS = 758
CHAPTER 73 Restrictive Lung Diseases / MEIR H. KRYGER = 769
CHAPTER 74 Neuromuscular Disorders / CHARLES F. P. GEORGE = 776
SECTION XIV Medical Disorders / CHRISTIAN GUILLEMINAULT = 783
CHAPTER 75 Parkinsonism / MICHAEL S. ALDRICH = 783
CHAPTER 76 Dementia / DONALD L. BLIWISE = 790
CHAPTER 77 Epileptic Seizure Manifestations During Sleep / MARGARET N. SHOUSE = 801
CHAPTER 78 Nocturnal Paroxysmal Dystonia / E. LUGARESI ; P. MONTAGNA ; F. CIRIGNOTTA = 815
CHAPTER 79 Central Neurogenic Hyperventilation / CHRISTOPHER R. JONES = 818
CHAPTER 80 Cardiac Function During Sleep / W. WARD FLEMONS ; S. GABRIELLE HORNE ; CHRISTIAN GUILLEMINAULT ; ANNE M. GILLIS = 824
CHAPTER 81 Cardiovascular Disease and Sleep / CHARLES F. P. GEORGE = 835
CHAPTER 82 Cardiac Arrhythmias During Sleep / ANNE M. GILLIS ; W. WARD FLEMONS = 847
CHAPTER 83 Gastrointestinal Disorders / WILLIAM C. ORR = 861
SECTION XV Psychiatric Disorders / J. CHRISTIAN GILLIN = 871
CHAPTER 84 The Anxiety Disorders / THOMAS W. UHDE = 871
CHAPTER 85 Mood Disorders / RUTH M. BENCA = 899
CHAPTER 86 Sleep and Schizophrenia / VINCENT P. ZARCONE, JR. ; KATHLEEN L. BENSON = 914
CHAPTER 87 Sleep in Eating Disorders / RUTH M. BENCA ; REGINA C. CASPER = 927
CHAPTER 88 Sleep and Psychoactive Drugs of Abuse and Dependence / J. CHRISTIAN GILLIN = 934
SECTION XVI Methodology / MARY A. CARSKADON = 943
CHAPTER 89 Monitoring and Staging Human Sleep / MARY A. CARSKADON ; ALLAN RECHTSCHAFFEN = 943
CHAPTER 90 Measuring Daytime Sleepiness / MARY A. CARSKADON = 961
CHAPTER 91 Monitoring Penile Erections During Sleep / J. CATESBY WARE ; MAX HIRSHKOWITZ = 967
CHAPTER 92 Ambulant Home Monitoring of Sleep and Its Disorders / ROGER J. BROUGHTON = 978
CHAPTER 93 Monitoring Respiratory and Cardiac Function / MEIR H. KRYGER = 984
CHAPTER 94 Monitoring Gastroesophageal Reflux During Sleep / WILLIAM C. ORR = 1008
CHAPTER 95 Light Treatment / MICHAEL TERMAN = 1012
INDEX = 1031
